2022
DOI: 10.1002/tox.23628
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Liver dysfunction and energy storage mobilization in traíra, Hoplias malabaricus (Teleostei, Erythrinidae) induced by subchronic exposure to toxic cyanobacterial crude extract

Abstract: Microcystins (MC) are hepatotoxic for organisms. Liver MC accumulation and structural change are intensely studied, but the functional hepatic enzymes and energy metabolism have received little attention. This study investigated the liver and hepatocyte structures and the activity of key hepatic functional enzymes with emphasis on energetic metabolism changes after subchronic fish exposure to cyanobacterial crude extract (CE) containing MC. The Neotropical erythrinid fish, Hoplias malabaricus, were exposed int… Show more

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Cited by 3 publications
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“…The reason for this result may be that the FM, 320 mg/kg and 160 mg/kg groups had an appropriate mucosal barrier to resist the invasion of anti-nutritional factors. ALT, ALP and AST concentrations in serum can rise as a result of liver injury ( 37 ). The activity of ALT, ALP and AST in groups 80 mg/Kg, 40 mg/Kg and control was significantly higher than that in the other groups.…”
Section: Discussionmentioning
confidence: 99%
“…The reason for this result may be that the FM, 320 mg/kg and 160 mg/kg groups had an appropriate mucosal barrier to resist the invasion of anti-nutritional factors. ALT, ALP and AST concentrations in serum can rise as a result of liver injury ( 37 ). The activity of ALT, ALP and AST in groups 80 mg/Kg, 40 mg/Kg and control was significantly higher than that in the other groups.…”
Section: Discussionmentioning
confidence: 99%