Liver biopsy: Complications in 1000 inpatients and outpatients

Percutaneous radiofrequency ablation of hepatocellular carcinoma abutting the diaphragm and gastrointestinal tracts with the use of artificial ascites: safety and technical efficacy in 143 patients

“…Traditionally, the presence of ascites was considered to increase the risk of sustained intraperitoneal hemorrhage from the hepatic surface by washing away thrombogenic material at the puncture site and decreasing the "tamponade effect" from the opposing parietal peritoneum against the liver [35]. However, the rate of bleeding complications was 0.7% in this study, which was equivalent to the 0.7% rate reported in a large study [33].…”

Noninvasive laboratory tests proposed for predicting cirrhosis in patients with chronic hepatitis C are also useful in patients with non-alcoholic steatohepatitis

“…However, biopsy is not suitable for repeated evaluations because it is costly, invasive, and associated with a risk of major complications (0.3-0.5%), including death (0.03-0.1%) [7,8]. Sampling error may lead to underestimation of underlying cirrhosis, especially when biopsy specimens are small or fragmented.…”

Magnetic resonance elastography (MRE) in assessing hepatic fibrosis: performance in a cohort of patients with histological data

“…The gold standard to monitor liver fibrosis remains liver biopsy, a relatively painful and invasive technique. Significant complications, defined as requiring hospital admission or prolonged hospital stay, occur in 1-5% of patients with a mortality rate of between 1:1000 and 1:10,000 [2][3][4]. In addition, liver biopsy is prone to sampling error because only 1:50,000 of the organ is sampled.…”