Liver and Bile Duct Infections

Masia, Ricard; Misdraji, Joseph

doi:10.1016/b978-0-323-44585-6.00011-4

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Cited by 5 publications

References 463 publications

(790 reference statements)

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Pancreatic and Biliary Tract Cancers

Ney,

Osei‐Bordom,

Garcia‐Sampedro

et al. 2024

Gastrointestinal Oncology ‐ a Critical Multidisciplinary Team Approach 2e

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Pancreatic and Biliary Tract Cancers

Ney,

Osei‐Bordom,

Garcia‐Sampedro

et al. 2024

Gastrointestinal Oncology ‐ a Critical Multidisciplinary Team Approach 2e

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Visceral larva Migrans in a Young Italian Patient: A Diagnostic Dilemma

Francalanci,

Manciulli,

Bandini

et al. 2023

Acta Parasit.

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Background The association of fever, focal hepatic lesions and peripheral hyper-eosinophilia (FHLH) can be observed in both infectious and non-infectious conditions. Fascioliasis, capillariasis, toxocariasis, all causes of visceral larva migrans (VLM), represent most of the former, whilst lymphomas, eosinophilic leukemias and mastocytosis belong in the non-infectious conditions. Methods We prospectively followed a young patient presenting with FHLH in the Tuscany region of Italy. Results The patient was subject to serological and parasitological examination in an attempt to clarify the origin of the lesions. Serologies for both Fasciola hepatica and Toxocara spp. were positive, with the latter presenting a higher index. We opted for treatment with a prolonged course of albendazole due to the serological results and being toxocariasis more frequent in our setting. The patient was then subject to radiological follow-up. The patient responded to treatment with albendazole as shown by a decrease in eosinophils, seronegativization for Toxocara spp., clinical and radiological improvement. Toxocariasis was hence considered the most likely diagnosis. Conclusions Parasitic infections cannot be disregarded in the presence of FHLH. Differential diagnosis between these parasitic infections can be challenging due to the presence of similar clinical presentations and serological cross-reactions, and follow-up of the patient is needed to ensure optimal treatment outcomes.

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