Live Video Mind-Body Program for Patients With Knee Osteoarthritis, Comorbid Depression, and Obesity: Development and Feasibility Pilot Study

Mace, Ryan A.; Greenberg, Jonathan; Lemaster, Nicole; Duarte, Brooke A.; Penn, Terence; Kanaya, Millan R.; Doorley, James; Burris, Jessica L.; Jacobs, Cale A.; Vranceanu, Ana‐Maria

doi:10.2196/34654

Cited by 4 publications

(1 citation statement)

References 112 publications

(117 reference statements)

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“…Other studies have used automated text messaging to deliver PROM questionnaires with a similar number of items to patient populations ranging from those with anterior cruciate ligament injuries to knee osteoarthritis. 7,22 Future work is needed to determine if the combination of validated short forms with SMS text messaging PROM collection systems may increase response rates in this younger, active patient population. Future work is also needed to determine if the 0 to 100 scale of the Short-WOSI is more easily interpreted by clinicians and/or patients when compared with the WOSI original 0 to 2100 scale.…”

Section: Discussionmentioning

confidence: 99%

Development and Validation of a Short-Form Version of the Western Ontario Shoulder Instability Scale (Short-WOSI)

Jacobs,

Ortiz,

Baumgarten

et al. 2023

Am J Sports Med

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Background: Patient-reported outcome measures (PROMs) have transitioned from primarily being used as research instruments to becoming increasingly used in the clinical setting to assess recovery and inform shared decision-making. However, there is a need to develop validated short-form PROM instruments to decrease patient burden and ease incorporation into clinical practice. Purpose: To assess the validity and responsiveness of a shortened version of the Western Ontario Shoulder Instability Index (Short-WOSI) when compared with the full WOSI and other shoulder-related PROM instruments. Study Design: Cohort study (diagnosis); Level of evidence, 2. Methods: This study was a secondary analysis of data collected as part of an institutional review board–approved, multicenter cohort of 1160 patients undergoing surgical stabilization for shoulder instability. The following PROMs were captured preoperatively and 2 years after surgery: WOSI, American Shoulder and Elbow Surgeons (ASES) score, the Single Assessment Numeric Evaluation (SANE), and 36-Item Health Survey (RAND-36). The cohort was split into 2 data sets: a training set to be used in the development of the Short-WOSI (n = 580) and a test set to be used to assess the validity and responsiveness of the Short-WOSI relative to the full WOSI, ASES, SANE, and RAND-36. Results: The Short-WOSI demonstrated excellent internal consistency before surgery (Cronbach α = .83) and excellent internal consistency at the 2-year follow-up (Cronbach α = .93). The baseline, 2-year, and pre- to postoperative changes in Short-WOSI and WOSI were closely correlated ( r > 0.90), with both demonstrating large effect sizes (Short-WOSI = 1.92, WOSI = 1.81). Neither the Short-WOSI nor the WOSI correlated well with the other PROM instruments before ( r = 0.21-0.33) or after ( r = 0.25-0.38) surgery. The Short-WOSI, WOSI, and SANE scores were more responsive than ASES and RAND-36 scores. Conclusion: The 7-item Short-WOSI demonstrated excellent internal consistency and a lack of floor or ceiling effects. The Short-WOSI demonstrated excellent cross-sectional and longitudinal construct validity and was similarly responsive over time as the full WOSI. Neither the Short-WOSI nor WOSI correlated with more general shoulder PROMs, underscoring the advantage of using instability-specific instruments for this population.

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Section: Discussionmentioning

confidence: 99%

Development and Validation of a Short-Form Version of the Western Ontario Shoulder Instability Scale (Short-WOSI)

Jacobs,

Ortiz,

Baumgarten

et al. 2023

Am J Sports Med

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The research protocol of unpacking the “mind” and “body” pathways of antidepressant effects of school children with obesity in Hong Kong

Miao,

Ning,

et al. 2024

Preprint

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Background This study will investigate the effects of Qigong, mindfulness, and low-intensity exercise on the mental and physical health of obese school children (6–18 years old). It seeks to unpack the mechanisms through which these mind-body interventions impact depressive symptoms in this population since these effects and the underlying pathways through which they exert their antidepressant effects remain unclear. Methods This protocol proposes a randomised controlled trial (RCT). It will recruit a sample of obese school children and randomly assign them to a qigong, mindfulness, low-intensity exercise, or control group first. Then, it will implement the interventions over a specified period and conduct pre- and post-intervention assessments to measure changes in depressive symptoms, weight, and psychological well-being. Quantitative measures will include standardised scales assessing depressive symptoms, cognitive function, and weight-related outcomes. Data analysis will involve regression and t-tests to examine interventions’ effects on depression and weight-related outcomes. Discussion This study expects to reveal the psychological and physiological mechanisms of the antidepressant effects of Qigong, mindfulness, and low-intensity exercise on obese school children by implementing this study, which will help develop more effective interventions to reduce the incidence of obesity. Ultimately, the findings may improve health outcomes in obese school children and contribute to developing healthcare strategies for this vulnerable population. Trial registration: ClinicalTrials.gov ID: NCT03615937.

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Smartphone App–Delivered Mindfulness-Based Intervention for Mild Traumatic Brain Injury in Adolescents: Protocol for a Feasibility Randomized Controlled Trial

Ledoux,

Zemek,

Cairncross

et al. 2024

JMIR Res Protoc

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Background Concussion in children and adolescents is a significant public health concern, with 30% to 35% of patients at risk for prolonged emotional, cognitive, sleep, or physical symptoms. These symptoms negatively impact a child’s quality of life while interfering with their participation in important neurodevelopmental activities such as schoolwork, socializing, and sports. Early psychological intervention following a concussion may improve the ability to regulate emotions and adapt to postinjury symptoms, resulting in the greater acceptance of change; reduced stress; and recovery of somatic, emotional, and cognitive symptoms. Objective The primary objective of this study is to assess the feasibility of conducting a parallel-group (1:1) randomized controlled trial (RCT) to evaluate a digital therapeutics (DTx) mindfulness-based intervention (MBI) in adolescents aged 12 to <18 years. The attention-matched comparator intervention (a math game also used in previous RCTs) will be delivered on the same DTx platform. Both groups will be provided with the standard of care guidelines. The secondary objective is to examine intervention trends for quality of life; resilience; self-efficacy; cognition such as attention, working memory, and executive functioning; symptom burden; and anxiety and depression scores at 4 weeks after concussion, which will inform a more definitive RCT. A subsample will be used to examine whether those randomized to the experimental intervention group have different brain-based imaging patterns compared with those randomized to the control group. Methods This study is a double-blind Health Canada–regulated trial. A total of 70 participants will be enrolled within 7 days of concussion and randomly assigned to receive the 4-week DTx MBI (experimental group) or comparator intervention. Feasibility will be assessed based on the recruitment rate, treatment adherence to both interventions, and retention. All outcome measures will be evaluated before the intervention (within 7 days after injury) and at 1, 2, and 4 weeks after the injury. A subset of 60 participants will undergo magnetic resonance imaging within 72 hours and at 4 weeks after recruitment to identify the neurophysiological mechanisms underlying the potential benefits from MBI training in adolescents following a concussion. Results The recruitment began in October 2022, and the data collection is expected to be completed by September 2024. Data collection and management is still in progress; therefore, data analysis is yet to be conducted. Conclusions This trial will confirm the feasibility and resolve uncertainties to inform a future definitive multicenter efficacy RCT. If proven effective, a smartphone-based MBI has the potential to be an accessible and low-risk preventive treatment for youth at risk of experiencing prolonged postconcussion symptoms and complications. Trial Registration ClinicalTrials.gov NCT05105802; https://classic.clinicaltrials.gov/ct2/show/NCT05105802 International Registered Report Identifier (IRRID) DERR1-10.2196/57226

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Live Video Mind-Body Program for Patients With Knee Osteoarthritis, Comorbid Depression, and Obesity: Development and Feasibility Pilot Study

Cited by 4 publications

References 112 publications

Development and Validation of a Short-Form Version of the Western Ontario Shoulder Instability Scale (Short-WOSI)

Development and Validation of a Short-Form Version of the Western Ontario Shoulder Instability Scale (Short-WOSI)

The research protocol of unpacking the “mind” and “body” pathways of antidepressant effects of school children with obesity in Hong Kong

Smartphone App–Delivered Mindfulness-Based Intervention for Mild Traumatic Brain Injury in Adolescents: Protocol for a Feasibility Randomized Controlled Trial

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