Live Image Processing Does Not Increase Adenoma Detection Rate During Colonoscopy: A Randomized Comparison Between FICE and Conventional Imaging (Berlin Colonoscopy Project 5, BECOP-5)

Abstract

This large randomized trial could not show any objective advantage of the FICE technique over conventional high-resolution endoscopy in terms of improved ADR.

Image-enhanced endoscopy technology in the gastrointestinal tract: What is available?

“…A study examining the impact of FICE in combination acetic acid in Barrett's esophagus proved a modest improvement in high-grade dysplasia detection compared to random biopsies [23]. Two large studies have shown that there is no additive benefit for the use of FICE in colorectal adenoma detection [24,25]. While characterization of colonic polyps reaches 87% when FICE with magnification is used [26].…”

Guidelines for an Optimum Screening Colonoscopy

“…Results of cap-fitted colonoscopy have been mixed [75][76][77][78]. Electronic highlighting strategies such as narrow band imaging [79][80][81][82][83][84], the Fujinon Intelligent ChromoEndoscopy System [85][86][87], and the Pentax i-scan System [88] have either been ineffective [80-83, 85, 86], had unconvincing study designs [84], or very low level adenoma detection in control groups [88]. Pancolonic chromoendoscopy is effective in improving the detection of diminutive adenomas [89] but adds time and inefficiency to procedure performance.…”

Recent Advances in Diagnostic Endoscopy for Colorectal Neoplasm

“…Furthermore, because of its variable setting functions (up to 10), the operator has flexibility in selection of the most suitable wavelengths for each examination. Although some randomized controlled trials have been conducted (Aminalai et al, 2010Chung et al, 2010, no one has yet demonstrated improvement in adenoma miss or detection rates compared with WLI. Autofluorescence imaging is an endoscopic technique for visualizing with reflected autofluorescence, which is emitted from an endogeneous fluorophore by exposing it to short wavelength excitation light (Fig.…”