Live birth and normal 1-year follow-up of a baby born after transfer of cryopreserved embryos from rescue intracytoplasmic sperm injection of 1-day-old oocytes

Neonatal outcome of early rescue ICSI and ICSI with ejaculated sperm

“…To salvage fertilization failure and overcome oocyte aging, early rescue ICSI has been performed 6 h post-insemination (9 h after oocyte retrieval) [3,4], and better fertilization, implantation, pregnancy and live birth rates were obtained when compared to other rescue methods such as partial zona dissection (PZD), subzonal insemination (SUZI) ( [5]; [6]) or day 1 rescue ICSI [7][8][9][10][11]. Chen et al [3] reported that reinsemination by ICSI of failed-fertilized IVF oocytes for 25 patient IVF cycles 6 h after initial insemination obtained a 70.3 % fertilization rate and 48.0 % clinical pregnancy rate and resulted in three sets of twins, eight singletons and one abortion.…”

Should all embryos from day 1 rescue intracytoplasmic sperm injection be transferred during frozen–thawed cycles?

“…Sperm defect, oocytes' abnormality, and disturbance in sperm-oocyte interaction may account for this infrequent situation. To overcome fertilization failure, some investigators have suggested to perform a day 1 intracytoplasmic sperm injection (ICSI) of unfertilized mature oocytes, the so-called ''rescue'' ICSI (2)(3)(4)(5). Although some pregnancies and live births have been reported following fresh (5)(6)(7) or frozen-thawed (3,5) embryo transfers (ET), this procedure is still controversial because of a high incidence of genetic abnormalities in the resulting embryos (7-9) and of a poor outcome (2, 10).…”

Comparison of fresh and vitrification frozen–thawed embryo transfer cycles after rescue intracytoplasmic sperm injection

“…Yuzpe et al [6], Singh et al [7], Esfandiari et al [8], and Morton et al [9] have all reported positive outcomes using fresh ET cycles. Yuzpe et al [6] and Lombardi et al [10] reported some successful pregnancies using frozen-thawed transfer cycles. However, they experienced less satisfactory clinical outcomes than with conventional IVF and ICSI cycles.…”

“…Rescue ICSI contributes to clinical pregnancies and births for some couples, using fresh embryo-transfer (ET) cycles or frozen-thawed ET cycles [6][7][8][9][10]. However, most studies have indicated that the outcomes after rescue ICSI are not ideal, especially using fresh ET cycles [11].…”