Littoral invertebrate communities (meio-and macrobenthos and zooplankton) were studied in seven types of macrophyte associations commonly encountered in Lake Ladoga : in reed (Phragmites) beds on sand, soft and hard bottoms, in associations with the prevalence of Potamogeton spp ., Carex spp ., and Equisetum fluviatile, and in diverse vegetation stands with e .g . Polygonum amphibium, Cicuta virosa, Typha latifolia and Eleocharis acicularis . Some of the studied habitats were affected by sewage pollution, others were in comparatively undisturbed areas . Statistically significant differences between invertebrate communities in the different macrophyte associations were found . In stepwise multiple linear regression analysis the following factors were identified as determinants of abundance of aquatic invertebrates in macrophyte associations : shoot density, plant dry weight biomass, periphyton biomass, periphyton chlorophyll a, periphyton primary production, and concentrations of Sr, Mg, Ca, P, Mn, Zn, Pb and Cu. Pollution was shown to have a minor effect on the composition of littoral invertebrate communities . It is not possible to determine one single principle factor responsible for the structure and density of invertebrates in macrophyte communities .