Abstract:Lithium is like a two-edged sword; it is on the one hand a unique drug with psychoactive potential as a mood stabilizer and on the other hand a burdensome drug which can cause multisystem toxicity to alter basic cellular function. Many drugs interact with lithium, increasing its blood level. For example, elevated lithium concentrations after the initiation of angiotensin-converting enzyme (ACE) inhibitors have been well documented in literaturesHowever interaction between angiotensin II type 1 receptor (AT1R) … Show more
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