Lithium <i>tert</i>‐butoxide/DMSO‐mediated Rapid Synthesis of Naphthalenes, Benzofurans, and Indoles

Wang, Zhihua; Cheng, Ling-Chao; He, Xinglei; Ye, Ke‐Yin

doi:10.1002/ajoc.202300135

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2024

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Cited by 2 publications

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“…In 2023, tert -butoxide was employed as a catalyst toward the synthesis of benzofuran heterocycles 103 in the presence of dimethyl sulfoxide solvent by Wang’s group 106 ( Scheme 31 ).…”

Section: Precedented Approachesmentioning

confidence: 99%

A Comprehensive Review on Benzofuran Synthesis Featuring Innovative and Catalytic Strategies

Mushtaq,

Zahoor,

Ahmad

et al. 2024

ACS Omega

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Benzofurans have intrigued both pharmaceutical researchers and chemists owing to the medicinal usage of their derivatives against copious diseasecausing agents (i.e., bacteria, viruses, and tumors). These heterocyclic scaffolds are pervasively encountered in a number of natural products and drugs. The everincreasing utilization of benzofuran derivatives as pharmaceutical agents persuaded the chemists to devise novel and facile methodological approaches to assemble the biologically potent benzofuran nucleus. This review summarizes the current developments regarding the innovative synthetic routes and catalytic strategies to procure the synthesis of benzofuran heterocycles with their corresponding mechanistic details, reported by several research groups during 2021−2023.

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“…In 2023, tert -butoxide was employed as a catalyst toward the synthesis of benzofuran heterocycles 103 in the presence of dimethyl sulfoxide solvent by Wang’s group 106 ( Scheme 31 ).…”

Section: Precedented Approachesmentioning

confidence: 99%

A Comprehensive Review on Benzofuran Synthesis Featuring Innovative and Catalytic Strategies

Mushtaq,

Zahoor,

Ahmad

et al. 2024

ACS Omega

View full text Add to dashboard Cite

show abstract

Unusual participation of O-propargyl group during the cyclization of 6-hydroxy-2-propargyl ethers of aryl chalcones: one-pot synthesis of 2-acyl-3-styrylbenzofuran and 7-aryldibenzo[b,d]furan-1,7-diols

Samyuktha,

Ethiraj,

Shanmugam

2023

New J. Chem.

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Lithium tert‐butoxide/DMSO‐mediated Rapid Synthesis of Naphthalenes, Benzofurans, and Indoles

Abstract: Herein, an efficient lithium tert‐butoxide/DMSO‐mediated rapid synthesis of naphthalenes, benzofurans, and indoles is reported. The anticipated aromatics and heteroaromatics are obtained in high yields within a few minutes, even in a decagram‐scale reaction.

Cited by 2 publications

References 52 publications

A Comprehensive Review on Benzofuran Synthesis Featuring Innovative and Catalytic Strategies

A Comprehensive Review on Benzofuran Synthesis Featuring Innovative and Catalytic Strategies

Unusual participation of O-propargyl group during the cyclization of 6-hydroxy-2-propargyl ethers of aryl chalcones: one-pot synthesis of 2-acyl-3-styrylbenzofuran and 7-aryldibenzo[b,d]furan-1,7-diols

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