Lithium anthraquinoids as catalysts in the ROP of lactide and caprolactone into cyclic polymers

Martínez, Cristina Ruiz; Pérez, Juana M.; Arrabal-Campos, Francisco M.; Rodríguez-Diéguez, Antonio; Choquesillo-Lazarte, Duane; Martínez-Lao, Juan Antonio; Ortuño, Manuel Á.; Fernández, Ignacio

doi:10.1039/d2py01076c

Cited by 3 publications

(1 citation statement)

References 57 publications

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“…Thus, UiO-66 NP must have played a role in the initiation step. Indeed, it is long known that lithium and transition metal complexes with Lewis acidity are carbonyl activators, and can serve as catalysts for the ringopening polymerizations 49,50 of cyclic esters [51][52][53][54] , carbonates 55 , and O-carboxyanhydrides 56,57 through a coordination-insertion mechanism. The UiO-66 NP is believed to be working in a similar way (Fig.…”

Section: Verification Of the Two-step Mechanism Of Uio-66-involved Ca...mentioning

confidence: 99%

A nanoscale MOF-based heterogeneous catalytic system for the polymerization of N-carboxyanhydrides enables direct routes toward both polypeptides and related hybrid materials

Liu,

Ren,

Zhang

et al. 2023

Nat Commun

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Synthetic polypeptides have emerged as versatile tools in both materials science and biomedical engineering due to their tunable properties and biodegradability. While the advancements of N-carboxyanhydride (NCA) ring-opening polymerization (ROP) techniques have aimed to expedite polymerization and reduce environment sensitivity, the broader implications of such methods remain underexplored, and the integration of ROP products with other materials remains a challenge. Here, we show an approach inspired by the success of many heterogeneous catalysts, using nanoscale metal-organic frameworks (MOFs) as co-catalysts for NCA-ROP accelerated also by peptide helices in proximity. This heterogeneous approach offers multiple advantages, including fast kinetics, low environment sensitivity, catalyst recyclability, and seamless integration with hybrid materials preparation. The catalytic system not only streamlines the preparation of polypeptides and polypeptide-coated MOF complexes (MOF@polypeptide hybrids) but also preserves and enhances their homogeneity, processibility, and overall functionalities inherited from the constituting MOFs and polypeptides.

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Section: Verification Of the Two-step Mechanism Of Uio-66-involved Ca...mentioning

confidence: 99%

A nanoscale MOF-based heterogeneous catalytic system for the polymerization of N-carboxyanhydrides enables direct routes toward both polypeptides and related hybrid materials

Liu,

Ren,

Zhang

et al. 2023

Nat Commun

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show abstract

Organocatalysts for -Lactide polymerization: 2-alkyl- and 2-aryl-1,1,3,3-tetramethylguanidines

Kamaraj,

Ganta,

Halima

et al. 2024

Molecular Catalysis

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Organocatalysts for L-Lactide Polymerization: 2-Alkyl- and 2-Aryl-1,1,3,3-Tetramethylguanidines

Kamaraj,

Ganta,

Halima

et al. 2024

Preprint

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Lithium anthraquinoids as catalysts in the ROP of lactide and caprolactone into cyclic polymers

Abstract: New lithium anthraquinoids 2b–d active in the synthesis of cyclic PLA and cyclic PCL have been synthesized and fully characterized.

Cited by 3 publications

References 57 publications

A nanoscale MOF-based heterogeneous catalytic system for the polymerization of N-carboxyanhydrides enables direct routes toward both polypeptides and related hybrid materials

A nanoscale MOF-based heterogeneous catalytic system for the polymerization of N-carboxyanhydrides enables direct routes toward both polypeptides and related hybrid materials

Organocatalysts for -Lactide polymerization: 2-alkyl- and 2-aryl-1,1,3,3-tetramethylguanidines

Organocatalysts for L-Lactide Polymerization: 2-Alkyl- and 2-Aryl-1,1,3,3-Tetramethylguanidines

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