Lithiasis in 1,313 Kidney Transplants: Incidence, Diagnosis, and Management

Cassini, Marcelo Ferreira; Cologna, Adauto José; Andrade, Murilo Ferreira de; Lima, Giovana; Albuquerque, U. Medeiros; Martins, Antônio Carlos Pereira; Tucci, S.

doi:10.1016/j.transproceed.2012.07.052

Cited by 46 publications

(32 citation statements)

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“…In some cases, conservative procedures are used. 1,2 In addition to these procedures, as shown here in 1 patient with secondary oxalosis and recurrence of urinary stones, a pyelovesicostomy was implemented, an uncommon and not yet discussed therapeutic intervention for patients with urolithiasis in the renal graft.…”

Section: Introductionmentioning

confidence: 98%

“…In the literature, the incidence rate varies from 0.2% to 2.1%. [1][2][3][4][5][6][7][8][9] With improvements in both graft and patient survival and the not negligible increase in the acceptance of marginal organs, clinicians will steadily be faced with more long-term complications, including urolithiasis, in renal grafts. 10,11 There are 2 possible ways for urinary stones to evolve in an allograft.…”

Section: Introductionmentioning

confidence: 99%

“…Either the calculi are present in the donor (these stones are detected perioperatively or they are considered to be, if detected later, new formations). 1,2 In general, there are more de novo formations than stones from donors. 1 Patients who develop stones in an allograft kidney usually do not present with typical symptoms of urolithiasis on grounds of the kidney's denervation, which contributes to a delayed diagnosis.…”

Section: Introductionmentioning

confidence: 99%

“…1,2 In general, there are more de novo formations than stones from donors. 1 Patients who develop stones in an allograft kidney usually do not present with typical symptoms of urolithiasis on grounds of the kidney's denervation, which contributes to a delayed diagnosis. 1,2,12 Nonetheless, to prevent further complications like sepsis, graft rejection, or significant graft impairment, early diagnosis and treatment are necessary.…”

Section: Introductionmentioning

confidence: 99%

“…1 Patients who develop stones in an allograft kidney usually do not present with typical symptoms of urolithiasis on grounds of the kidney's denervation, which contributes to a delayed diagnosis. 1,2,12 Nonetheless, to prevent further complications like sepsis, graft rejection, or significant graft impairment, early diagnosis and treatment are necessary. After diagnosis, treatment of calculi in the allograft kidney is challenging because of multiple factors.…”

Section: Introductionmentioning

confidence: 99%

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Friedersdorff

El-Bandar²,

Busch³

et al. 2017

Exp Clin Transplant

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Objectives: Urinary calculi rarely occur in renal transplant. However, because of peculiarities shown with renal allografts, a prudent approach is necessary to prevent further complications or even graft failure. There are no well-established guidelines for urolithiasis in renal grafts regarding adequate therapy selection. In the present article, different therapeutic interventions are discussed, including in 1 case a pyelovesicostomy as an uncommon intervention. Materials and Methods: We retrospectively reviewed data of 1115 patients who underwent renal transplant between January 2002 and December 2014 for urolithiasis in different databases.Results: Eight patients in our study group formed urinary calculi after renal transplant. Only 5 patients were included, with incidence rate of 0.45%, since 3 patients received transplants elsewhere. Time between transplant and diagnosis ranged from 2 to 98 months. Extracorporeal shock wave lithotripsy (50%) was the most common intervention, followed by ureterorenoscopy (29%) and percutaneous nephrolithotomy (16%). One patient required 20 interventions due to recurrent urinary stones, necessitating an alternative procedure. In this case, a pyelovesicostomy was performed (an uncommon and previously not performed procedure for urolithiasis after renal graft). All patients were stone free at last follow-up. Conclusions: In contrast to other studies, renal stones from donors were not observed. Treatment took into account stone size, number, and localization, similar to the approach in the general population. However, alternative procedures, especially pyelovesicostomy, could be considered in patients with recurrent urolithiasis and who require multiple interventions.

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Section: Introductionmentioning

confidence: 98%