“…There are literature-based methods that have addressed association of genes to disease based on co-occurrences for a set of articles defined by a user query (Rebholz-Schuhmann et al, 2007;Tsuruoka et al, 2008) or that rely on matching of MeSH profiles (Cheung et al, 2012;Xiang et al, 2013). Other methods use indirect relations from co-occurrence analysis (Frijters et al, 2010) or based on interaction networks (Gonzalez et al, 2006;Özgür et al, 2008). Some combine different sources of information including the literature, such as Endeavour (Aerts et al, 2006), DisGeNET (Bauer-Mehren et al, 2010), G2D (Perez-Iratxeta et al, 2005), MimMiner (van Driel et al, 2006), PolySearch (Cheng et al, 2008) or the approach proposed by Tiffin et al (2005).…”