Listeria monocytogenes Endophthalmitis

Bagnarello, Adolfo G.; Berlin, Allison J.; Weinstein, Allan J.; McHenry, Martin C.; O’Connor, Patrick S.

doi:10.1001/archopht.1977.04450060090008

Cited by 23 publications

(13 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In all cases the cause of bacterial endophthalmitis was determined by recovering the organism from cultures of intraocular fluids. Six of the 17 published cases of L. monocytogenes endophthalmitis occurred in immunocompromised patients (2,5,7,20,22,25), 6 occurred in elderly patients with good physical health (1,4,14,15,17,19), and the remaining 5 cases affected young healthy individuals (6,8,12,13,29). Our patient had several potentially predisposing factors, including laryngeal carcinoma and immunosuppressive therapy.…”

Section: Case Reportmentioning

confidence: 77%

Endophthalmitis Caused by Listeria monocytogenes

Betriú¹,

Fuentemilla

Méndez

et al. 2001

J Clin Microbiol

View full text Add to dashboard Cite

Listeria monocytogenes was isolated from the aqueous chamber of an immunodepressed patient with acute hypertensive uveitis, who developed a dark hypopyon and pigment dispersion. No extraocular septic focus was found. Treatment was successful with intravitreal vancomycin, anterior chamber irrigation with vancomycin, orally administered ciprofloxacin, and topical fortified vancomycin. CASE REPORTA 62-year-old man presented to the emergency department with pain, redness, and decreased vision in the left eye. The patient had a history of laryngeal carcinoma, for which he had undergone laryngectomy and had been treated with radiation therapy and steroids. Examination of the eye on admission revealed acute hypertensive uveitis, and treatment with corticosteroids was begun but did not provide significant improvement. The patient developed a dark hypopyon with pigment dispersion and uveal ectropion. A differential diagnosis was made between endogenous endophthalmitis and a neoplastic process of the ciliary body (either primary ciliary body melanoma or metastatic melanoma from larynx carcinoma). Results from laboratory studies were unremarkable, except for the leukocyte count (14,030/mm 3 with 77% polymorphonuclear neutrophils). The chest X ray was normal. Blood cultures were negative. An ultrasound scan of the eye showed dispersion of echoes, and no evidence of retinal detachment was noted. B-scan ultrasonography revealed inflammatory deposition and pigmentary epithelium detachment. No proliferation was detected in the stromal iris.Anterior chamber paracentesis was performed and submitted for culture and histopathology. Cytological examination showed polymorphonuclear leukocytes and no evidence of neoplastic cells. Because the patient reported a history of penicillin allergy, combined treatment with oral administration of ciprofloxacin (750 mg twice a day), anterior chamber irrigation with vancomycin, and intravitreal vancomycin (1 mg) was started. Topical fortified vancomycin (1 g) and corticotherapy were also applied. The patient's condition improved with treatment. Within 7 days, the hypopyon disappeared and the intraocular pressure decreased. However, visual acuity was limited to appreciation of hand motion, because of a severe corneal edema and a cataract which developed in the patient's left eye.A small amount of fluid obtained by aspiration from the anterior chamber was directly plated onto blood agar and chocolate agar and distributed into aerobic and anaerobic blood culture bottles processed by the BACTEC 9050 system (Becton Dickinson Microbiology Systems, Cockeysville, Md.). Gram staining was performed and no organisms were observed. After a 24-h incubation of plates at 35°C in a 5% CO 2 -enriched atmosphere, catalase-positive, gram-positive coccobacilli grew, producing beta-hemolysis on blood agar. The isolate was identified as Listeria monocytogenes by both the Wider system (Francisco Soria Melguizo, S.A., Madrid, Spain) and the API Listeria system (bioMérieux, Marcy l'Etoile, France). Pure culture of L. mon...

show abstract

Section: Case Reportmentioning

confidence: 77%

Endophthalmitis Caused by Listeria monocytogenes

Betriú¹,

Fuentemilla

Méndez

et al. 2001

J Clin Microbiol

View full text Add to dashboard Cite

show abstract

“…Two cases of cor neal abscess have been reported [4,5]. L. monocytogenes has also been implicated in the genesis of iridocyclitis [6], though without bacteriological evidence, and in acute chorio retinitis [7], Endophthalmitis is exceptional; only 7 cases have been published [8][9][10][11][12][13][14]. A few common characteristics should be stressed:…”

Section: Discussionmentioning

confidence: 99%

“…Vitritis is some times, but not always, present [10][11][12][13]. Several authors emphasize the progressive brownish coloration of the hypopyon [5,12,13].…”

Section: Discussionmentioning

confidence: 99%

“…Although L. monocytogenes seems to be able to penetrate into the epithelial cells of the con junctiva and cornea and to proliferate before cellular lysis [20,21], it probably does not pen etrate through the corneal stroma. Although in 2 cases [10,14] an exogenous origin was suspect ed because of the occurrence of a corneal abra sion. the endogenous route, from the intestinal reservoir, is nevertheless favored.…”

Section: Discussionmentioning

confidence: 99%

“…could induce localization in the eye, by the circulatory way. In a few cases [8,10,13], the mode of contamination was thought to be ali mentary. In the case reported here the investi gation gave negative results as did also a cul ture of feces and an assay for serum antibodies.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

<i>Listeria monocytogenes</i> Endophthalmitis in a Renal-Transplant Patient Receiving Ciclosporin

Algan¹,

Jonon

George³

et al. 1990

Ophthalmologica

View full text Add to dashboard Cite

Endophthalmitis due to Listeria monocytogenes developed suddenly in a 52-year-old man receiving immunosuppressive therapy for a renal transplantation carried out 2 months previously. The treatment combined low doses of ciclosporin and prednisone. The initial clinical picture was of acute hypertensive uveitis with hypopyon. Despite prompt paracentesis and appropriate antibiotic therapy, the long-term course was unfavorable, and enucleation became necessary. The occurrence of listeriosis is classic in renal-transplant recipients, but no ocular form has been reported hitherto.

show abstract

Akute Iritis, akute Iridozyklitis

Neubauer¹

1981

Uveitis

View full text Add to dashboard Cite

Listeria monocytogenes Endophthalmitis

Cited by 23 publications

References 25 publications

Endophthalmitis Caused by Listeria monocytogenes

Endophthalmitis Caused by Listeria monocytogenes

<i>Listeria monocytogenes</i> Endophthalmitis in a Renal-Transplant Patient Receiving Ciclosporin

Akute Iritis, akute Iridozyklitis

Contact Info

Product

Resources

About