List of Main Advances in the Context of Cystic Fibrosis: Systematic Review

Abstract

Cystic fibrosis is a genetic, chronic, progressive and lethal disease, which can be previously diagnosed by the heel prick test. To analyze the main aspects of mucoviscidosis in terms of historical, epidemiological, genetic, pathogenic, clinical features, diagnosis and treatment. This is a systematic review in accordance with the PRISMA statement. The search was carried out in the MEDLINE, SciELO, SCOPUS and LILACS databases. The research was carried out independently by two researchers. Original articles were selected that addressed the object of study and published in Portuguese and English, and 38 articles were selected for qualitative analysis. Great advances were noted in the respective aspects already mentioned above, mainly in the focus on the quality of life and survival of patients, since in the last 80 years notable achievements have been obtained in terms of multidisciplinary treatment. It is concluded that it is essential to carry out new studies, especially in the long term, in order to increase survival and perhaps find a cure for this pathology.