List-mode motion tracking for positron emission tomography imaging using low-activity fiducial markers

Abstract

Motion correction in positron emi (PET) imaging may benefit from an accurate patient motion during the image acquisition. feasibility to detect and record the motion of markers during PET scans. We developed an it that can track the three-dimensional (3D) moti fiducial markers while surrounded by high ph activity from a patient undergoing PET imag techniques were used to simulate a 92.5-kBq 22 N sinusoidally in 3D. The simulated events were c mode data from patients undergoing cardiac order to test the algorithm. In experiment external 22 Na markers were placed on a dynam with an initial activity of approximately 680 M cardiac insert. We tracked the motion of tho simulating breathing motion and patient drift w Results from simulations show that a 92.5-kB tracked in 3D at a frequency of 2 Hz with an ac and a precision of 0.8 mm. The phantom st confirms that the algorithm can track both brea motion. The relative accuracy of the tracking and the precision was 0.8 mm. In conclusion, w an algorithm that can track the 3D motio positron-emitting markers during PET imag information might prove useful in develop correction schemes in clinical PET imaging.

Clinical comparison of the positron emission tracking (PeTrack) algorithm with the real‐time position management system for respiratory gating in cardiac positron emission tomography

“…The conditions in this work, therefore likely evaluated PeTrack performance under one of the most challenging settings. Regardless, this and other work have demonstrated feasibility in clinical practice, especially for the postbolus stages of a cardiac acquisition. Büther et al did not report similar difficulties while tracking radioactive fiducial markers in projection space although they reported using markers with activity that was roughly three times greater than that used in this study.…”

“…29 The algorithm has been recently adapted for use in PET studies and several preliminary studies have previously been presented at conferences. 30,31 This system relies only on the use of a lowactivity positron-emitting fiducial marker placed on the patient's chest and within the PET field of view. In this study, PeTrack was used to generate one-dimensional respiratory signals from its three-dimensional motion signal; an approach which has been suggested to be more robust in the presence of breathing irregularities compared to one-dimensional signals which most respiratory monitoring systems provide.…”

“…The positron emission tracking (PeTrack) algorithm is a hybrid data‐driven system which was originally designed for respiratory‐gated, external‐beam radiotherapy . The algorithm has been recently adapted for use in PET studies and several preliminary studies have previously been presented at conferences . This system relies only on the use of a low‐activity positron‐emitting fiducial marker placed on the patient’s chest and within the PET field of view.…”

Data-Driven Patient Motion Compensation in Cardiac Positron Emission Tomography

“…PeTrack performance under one of the most challenging settings. Regardless, this and other work 157,166 have demonstrated feasibility in clinical practice, especially for the postbolus stages of a cardiac acquisition. Büther and colleagues 122 did not report similar difficulties while tracking radioactive fiducial markers in projection space although they reported using markers with activity that was roughly three times greater than those in this study.…”