Lissencephaly in two brothers detected by US

Abstract

We report on two cases of lissencephaly in two brothers studied by high frequency ultrasound and subsequently confirmed by CT and, in one case, by post-mortem study. In addition to well known sonographic and CT signs described in the literature, a typical structural change of the brain (named "pseudo-liver") was detected using high-frequency sonography.

Sonografische Diagnose von Hirnfehlbildungen. Teil 3: Balkenagenesie – Migrationsstörungen

“…The brain parenchyma exhibits a liver-like internal reflex pattern (• ▶ Fig. 8) [15]. Occasionally an echogenic focal increase appears the periventricular region which corresponds to heterotopia (• ▶ Fig.…”

“…Das Hirnparenchym hat ein leberähnliches Binnenreflexmuster (• ▶ Abb. 8)[15]. Periventrikulär kann man gelegentlich fokale Echogenitätsvermehrungen finden, die Heterotopien entsprechen (• ▶ Abb.…”