Liquid-phase oxidation of ethyl lactate to pyruvate over suspended oxide catalysts

MoO3–TiO2 synergy in oxidative dehydrogenation of lactic acid to pyruvic acid

“…3,4 Scheme 1 depicts the large number of chemical products that can be obtained from LA. Catalytic dehydrogenation of LA to pyruvic acid (PyA) is of considerable importance for the production of L-amino acids, 5 cyanoacrylate adhesives, 6 perfumes, food additives, dietary and weightcontrol supplements, nutraceuticals, antioxidants 7 and photoresistant solvents for electronic processing. 8 The current industrial process for the production of PyA involves the stoichiometric dehydrative decarboxylation of tartaric acid.…”

Oxidation of Alcohols with Molecular Oxygen

“…Some oxides and mixed oxides such as TiO 2 or ZrO 2 that are rarely used as oxidation catalysts were active and highly selective in the transformation of ethyl lactate to pyruvate [166]. These selectivities, however, fell at high conversion such that the best yield was only 50%.…”

Enhancement of Catalytic Activity on Pd/C and Te–Pd/C During the Oxidative Dehydrogenation of Sodium Lactate to Pyruvate in an Aqueous Phase Under Pressurized Oxygen

“…By contrast, such successive reactions can be suppressed in liquid phase conversion due to the lower reaction temperature. Hayashi et al have developed catalytic conversions of lactic acid to pyruvic acid in an aqueous phase [10][11][12] coupled with ethyl lactate in an organic solution [13]. In the former conversion, they found no absorption of oxygen in the attempted oxidative dehydrogenation of lactic acid to pyruvic acid on Pd/C while a spectacular change in the oxidation activity in favor of pyruvic acid was observed in the presence of Pd/C that had been doped by either lead, bismuth or tellurium at 363 K [10][11][12].…”

“…If the oxidative dehydrogenation of lactic acid is examined using a typical autoclave, pH electrode, pH-adjustment apparatus and so on, which are suitable for the high-pressure study, should be attached to the autoclave. In the oxidative dehydrogenation of ethyl lactate in an organic solution at 403 K, it was reported that various single and binary oxides such as TiO 2 , ZrO 2 , SnO 2 , and SnO 2 -MoO 3 were highly selective catalysts for the production of ethyl pyruvate [13]. Since adsorption of molecular oxygen on the surface of the oxide catalysts was confirmed in these catalytic reactions [13], the employment of oxygen pressurization could possibly enhance the catalytic activity.…”

“…In the oxidative dehydrogenation of ethyl lactate in an organic solution at 403 K, it was reported that various single and binary oxides such as TiO 2 , ZrO 2 , SnO 2 , and SnO 2 -MoO 3 were highly selective catalysts for the production of ethyl pyruvate [13]. Since adsorption of molecular oxygen on the surface of the oxide catalysts was confirmed in these catalytic reactions [13], the employment of oxygen pressurization could possibly enhance the catalytic activity. However, the employment of a stainless steel autoclave for oxidative dehydrogenation of TiO 2 led to a loss of catalytic activity [14].…”