Liquid Nitrogen Spray Cryotherapy in the Esophagus Is Performed With Minimal Bleeding Risk Regardless of Concurrent Antithrombotic Therapy

Sharma, Neil; Perisetti, Abhilash; Leibowitz, Randy M.; Sehmbhi, Mantej; Park, Erica; Malik, Zubair A.; Mushtaq, Kamran R.; Zelt, Christina M.; Talabiska, Nicholas J.; Klein, Jeremy; Hogan, Carolyn T.; Smith, Michael S.

doi:10.1016/j.gie.2022.04.950

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“…Moreover, a study using a low-pressure portable CO 2 cryosurgery system on HGD or early adenocarcinoma in BE recorded 50% complete reversal of intestinal metaplasia for all Barrett's patients, 86% for HGD, and 84% for LGD, while no serious complications were noted, highlighting the CO 2 system safety and efficiency as an alternative endoscopic ablative modality for Barrett's dysplasia, carcinoma, and in refractory disease (187). A study by Sharma et al (188) on liquid N 2 -based cryosurgery quantified the risk of significant bleeding events in patients either with or without concurrent antithrombotic therapy applied in cardiovascular disease management and confirmed that major bleeding complications are extremely rare with no significant increases in transfusion and hospitalization rates, overall supporting current practice. Interestingly, evidence from the study of in vivo 38: 1-39 (2024) Figure 11.…”

Section: (C) Schematic Representation Of Changes Of Histological Zone...mentioning

confidence: 99%

Cryogenic Media in Biomedical Applications: Current Advances, Challenges, and Future Perspectives

MOKBEL,

KODRESKO,

GHAZAL

et al. 2023

In Vivo

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This paper explores the crucial role of cryogenic mediums in driving breakthroughs within the biomedical sector. The objective was to investigate, critically discuss, and present the current knowledge and state-of-the-art practices, along with the challenges and perspectives of the most common applications. Through an extensive literature review, this work aims to supplement existing research, offering a comprehensive and up-to-date understanding of the subject. Biomedical research involving cryogenic mediums is advancing on multiple fronts, including the development of advanced medical technologies, clinical treatments for life-threatening conditions, high-quality biospecimen preservation, and antimicrobial interventions in industrial food processing. These advances open new horizons and present cutting-edge opportunities for research and the medical community. While the current body of evidence showcases the impressive impact of cryogenic mediums, such as nitrogen, helium, argon, and oxygen, on

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Section: (C) Schematic Representation Of Changes Of Histological Zone...mentioning

confidence: 99%

Cryogenic Media in Biomedical Applications: Current Advances, Challenges, and Future Perspectives

MOKBEL,

KODRESKO,

GHAZAL

et al. 2023

In Vivo

View full text Add to dashboard Cite

show abstract

Liquid Nitrogen Spray Cryotherapy in the Esophagus Is Performed With Minimal Bleeding Risk Regardless of Concurrent Antithrombotic Therapy

Cited by 1 publication

References 0 publications

Cryogenic Media in Biomedical Applications: Current Advances, Challenges, and Future Perspectives

Cryogenic Media in Biomedical Applications: Current Advances, Challenges, and Future Perspectives

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