Liquid-Nitrogen Neuropathy

Neurological Complications of Cryosurgery

“…The few cases reported, however, warn that certain superficially located nerves in acral distribution are susceptible to injury. Nix reported two cases. In one the patient developed a persistent sensory neuropathy following the treatment of several verrucae on the palmar and medial aspects of the proximal phalanx of the second digit in the form of anesthesia to light touch and pinprick in the entire medial half of the affected finger distal to the point of treatment.…”

“…Not infrequently secondary infection, hypo‐ and hyperpigmentation, telangiectasia, milia, and scars occur. Rare complications that have been reported are pyogenic granuloma, hypertrophic scarring in a patient with cryoglobulinemia, precipitation of cold urticaria, poorly healing ulcers of the lower extremities, cardiac arrest, and peripheral neuropathies,.…”

Axonal Neuropathy in Severe SARS-CoV-2 Infections Is Multicausal

“…4 In addition, 2 other cases of digital nerve injury after liquid nitrogen cryotherapy have been reported as well. 5 In the published literature, a cranial neuropathy has not been described secondary to liquid nitrogen exposure for cosmetic dermatologic procedure.This unique case expands on the literature of unintended iatrogenic nerve injuries from liquid nitrogen therapy, particularly of cranial neuropathies. In our case, liquid nitrogen was applied to 3 locations-the left anterolateral nose, inferior to the left eye, and anterior to the left ear.…”

“…4 In addition, 2 other cases of digital nerve injury after liquid nitrogen cryotherapy have been reported as well. 5 In the published literature, a cranial neuropathy has not been described secondary to liquid nitrogen exposure for cosmetic dermatologic procedure.…”

Hemorrhagic Bullae After Cryosurgery in a Patient With Hemophilia A

“…Pigmentary alteration is relatively common and normally results in hypopigmentation 5 . Although neurologic complications are rare, multiple reports of self‐limited nerve damage after cryosurgery are documented 6–8 . Infection, syncope, pyogenic granuloma, abnormal scarring, alopecia, cartilage necrosis, and insufflation of soft tissue are rare but possible complications 2 .…”