Liquid - liquid extraction of matrine using TRPO/cyclohexane reverse micelles

Abstract

-Reverse micellar extraction has been widely used in the purification of biomolecules. However, reverse micelles formed by ionic surfactants can only be employed for the extraction of biomolecules that are charged in the extraction system with the electrostatic interaction between surfactants and solutes as the driving force. In this study, the extraction of matrine by using reverse micelles formed by non-ionic TRPO surfactants was studied. Theoretical analysis and experimental results demonstrated that the driving force of the extraction is the coordination forces between matrines and TRPOs. Using this coordination-based reverse micellar extraction, matrine can be efficiently separated from oxymatrine and other components in the raw matrine materials. Experimental studies showed that the factors affecting matrine extraction include pH value and TRPO concentration. The existence of ions in the system does not affect the partition coefficient significantly and the addition of a small amount of chloroform in the solution of reverse micelles was found to improve the extraction significantly.

Functionalization of sol-gel coatings with organophosphorus compounds for prosthetic devices

“…In addition, we observed the appearance of a new band at 1256 cm -1 in the functionalized synthesis. The literature identifies this signal between 1320 and 1140 cm -1 with the stretching vibration of a P=O bond [23][24][25]. The appearance of this bond indicates that the P-based compounds were incorporated into the synthesis.…”

Extraction of matrine from soil with matrix solid‐phase dispersion by molecularly imprinted polymers derived from lignin‐based Pickering emulsions

“…Although some of these methods can reach low LODs, sample pretreatment should be used before detection for enriching, purifying, and extracting matrine in different matrix to eliminate impurity interference. In recent years, some pretreatment methods have been reported, including LLE , SPE , and liquid membrane extraction . However, these methods also have some problems, such as large consumption of organic solvents, low selectivity of detection, complex and time‐consuming extraction processes, etc.…”

Induction of Depression Model in Mice: Implication of Different Reserpine Doses

“…Reserpine appears naturally in the dried roots of plants such as Rauwolfia Serpentina and Vomitoria. It is an indole alkaloid antipsychotic and antihypertensive drug that has been used for the control of high blood pressure and for the relief of psychotic symptoms (Dong et al, 2009 andRanganath et al, 2013). The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings.…”