Liquid–liquid equilibria of water+2,3-butanediol+isobutanol at several temperatures

Wu, Yanyang; Pan, De-Tao; Zhu, Junwen; Chen, Kui; Wu, Bin; Ji, Li‐Jun

doi:10.1016/j.fluid.2012.04.018

Cited by 22 publications

(12 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(°C) Refs. Ethyl acetate 25 0.17–0.28 0.22–0.63 1.3–2.8 0.897 77.1 [ 59 ] Butyl acetate 25 0.13–0.27 0.56–0.62 2.31–4.26 0.882 126 [ 60 ] 1-Butanol 25 0.55–0.82 1.23–1.62 1.51–2.95 0.81 117.7 [ 61 ] Isobutanol 25 0.51–0.66 1.45–1.55 2.27–2.92 0.802 108 [ 62 ] 2-Ethyl-1-hexanol 27 0.08–0.52 1.26–1.81 2.41–20.73 0.831 184.6 [ 63 ] Oleyl alcohol 27 0.01–0.37 2.66–6.52 7.24–421.9 0.855 348.02 [ 64 ] …”

Section: Resultsmentioning

confidence: 99%

Purification of 2,3-butanediol from fermentation broth: process development and techno-economic analysis

Harvianto

Haider

Jiang

et al. 2018

Biotechnol Biofuels

View full text Add to dashboard Cite

Background2,3-Butanediol (2,3-BDO) is a synthetic chemical compound that also can be produced by biomass fermentation, which is gaining share in the global market as an intermediate product for numerous applications, i.e. as liquid fuel or fuel additive. Several metabolic engineering fermentation strategies to enhance the production of 2,3-BDO were developed. However, the recovery of 2,3-BDO from its fermentation broth remains a challenge due to its low concentration and its solubility in water and other components. Thus, a cost-effective recovery process is required to deliver the required purity of 2,3-BDO. This paper presents a new process development and techno-economic analysis for 2,3-BDO purification from a fermentation broth.ResultsConventional distillation and hybrid extraction-distillation (HED) processes are proposed in this study with detailed optimization and economic analysis. Particularly, a systematic solvent selection method was successfully implemented to determine a good solvent for the proposed HED configuration based on numerous experimental data obtained with each solvent candidate. NRTL and UNIQUAC property methods were evaluated to obtain binary interaction parameters of 2,3-BDO through rigorous Aspen Plus regression and validated using experimental data. Total annual cost (TAC)-based optimization was performed for each proposed configuration. Even though the HED configuration required 9.5% higher capital cost than conventional distillation, placing an extraction column before the distillation column was effective in removing water from the fermentation broth and significantly improved the overall process economics.ConclusionsOleyl alcohol was found to be the most suitable solvent for the HED of 2,3-BDO due to its high distribution coefficient and high selectivity. The proposed HED drastically reduced reboiler duty consumption and TAC by up to 54.8 and 25.8%, respectively. The proposed design is expected to be used for the commercial scale of 2,3-BDO production from fermentation process.Electronic supplementary materialThe online version of this article (10.1186/s13068-018-1013-3) contains supplementary material, which is available to authorized users.

show abstract

Section: Resultsmentioning

confidence: 99%

Purification of 2,3-butanediol from fermentation broth: process development and techno-economic analysis

Harvianto

Haider

Jiang

et al. 2018

Biotechnol Biofuels

View full text Add to dashboard Cite

show abstract

“…Also, a proper solvent plays a key role because the solvent being used dictates the efficiency of separation and the overall process economy. To this purpose, various solvents have been studied for the recovery of the 2,3-BDO and water mixture. − Birajdar et al report that C 4 –C 6 alcohols are potentially effective for the extraction of 2,3-BDO. 4-Methyl-2-pentanol has been chosen in the current study as a solvent for the extraction of 2,3-BDO.…”

Section: Introductionmentioning

confidence: 99%

Liquid–Liquid Equilibrium Measurements for the Ternary System of Water/2,3-Butanediol/4-Methyl-2-pentanol at Various Temperatures

et al. 2019

View full text Add to dashboard Cite

Liquid−liquid equilibrium (LLE) of a ternary mixture of water, 2,3-butanediol, and 4-methyl-2-pentanol has been measured at three different temperatures (298.2, 308.2, and 318.2 K) under atmospheric pressure. The experimentally measured solubility and tieline data for the two-phase system were used to construct a ternary phase diagram at each temperature. With the experimental data, the distribution coefficients and separation factors were also calculated and Othmer− Tobias and Hand plots were used to verify the consistency of the measured data. The universal quasichemical (UNIQUAC) and nonrandom-two liquid (NRTL) models were used for the LLE, and the rootmean-square deviation values between the calculated and experimental data were less than 1.21% by the UNIQUAC model and less than 1.96% by the NRTL model, indicating that both model calculations provide excellent agreement with the experimentally measured LLE data in the present study.

show abstract

“…Several alternative techniques for the separation of 2,3-BDO from the fermentation broth have been proposed, including pervaporation, , reactive extraction, liquid–liquid extraction, and salting-out extraction . However, each technology has certain limitations in terms of its applicability to the commercial-scale production of 2,3-BDO.…”

Section: Introductionmentioning

confidence: 99%

Cost- and Energy-Efficient Butanol-Based Extraction-Assisted Distillation Designs for Purification of 2,3-Butanediol for Use as a Drop-in Fuel

Haider

Harvianto²,

Qyyum

et al. 2018

ACS Sustainable Chem. Eng.

View full text Add to dashboard Cite

Butanediol has attracted interest as a promising drop-in fuel, mainly due to its high antiknock index and high heating value. Microbial production of 2,3-butanediol is considered more environmentally friendly and sustainable than chemical-based production methods. However, to achieve the 99% purity required for use as fuel, the dehydration and purification steps associated with the microbial production process consume tremendous amounts of energy. This high energy consumption limits the feasibility of the microbial production process at the commercial scale. A commercially feasible and sustainable 2,3-butanediol production process is proposed based on an energy efficient extraction-assisted distillation scheme. On the basis of economic, technical, and environmental considerations, isobutyl alcohol and 1-butanol were chosen as suitable solvents for the proposed scheme. Regression analysis and data validation were applied to verify the incorporated experimental data which was then used in the well-established commercial process simulator Aspen Plus. Results indicate that the overall energy efficiency of the purification step of the microbial 2,3-butanediol production process can be improved greatly, with up to 24.5% and 31.3% reductions in total annualized cost for the isobutyl alcohol-and 1-butanol-based designs, respectively.

show abstract

Liquid–liquid equilibria of water+2,3-butanediol+isobutanol at several temperatures

Cited by 22 publications

References 14 publications

Purification of 2,3-butanediol from fermentation broth: process development and techno-economic analysis

Purification of 2,3-butanediol from fermentation broth: process development and techno-economic analysis

Liquid–Liquid Equilibrium Measurements for the Ternary System of Water/2,3-Butanediol/4-Methyl-2-pentanol at Various Temperatures

Cost- and Energy-Efficient Butanol-Based Extraction-Assisted Distillation Designs for Purification of 2,3-Butanediol for Use as a Drop-in Fuel

Contact Info

Product

Resources

About