“…Techniques that have been applied to the analysis of phenols and organic acids in cigarette smoke include gas chromatography, 20,24,[28][29][30][31][36][37][38][39][40][41] high performance liquid chroma-tography (HPLC), 21,22,[32][33][34][35]36 and capillary electrophoresis. 36 Most GC 20,27,[29][30][31][37][38][39][40][41] and some HPLC [32][33][34]36 methods require derivatization of the phenols or organic acids and extensive sample preparations, including solvent partitioning, column chromatography, 42 solid-phase extraction, [43][44][45] and acid-base extraction, prior to chromatography.…”