Liquid biopsy: Comprehensive overview of circulating tumor DNA (Review)
Qian Ge,
Zhi-Yun Zhang,
Suo-Ni Li
et al.
Abstract:Traditional tumor diagnosis methods rely on tissue biopsy, which can be invasive and unsuitable for long-term monitoring of tumor dynamics. The advent of liquid biopsy has notably improved the overall management of patients with cancer. Liquid biopsy techniques primarily involve detection of circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA). The present review focuses on ctDNA because of its significance in tumor diagnosis, monitoring and treatment. The use of ctDNA-based liquid biopsy offers se… Show more
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