Liposome-based multifunctional nanoplatform as effective therapeutics for the treatment of retinoblastoma

Liu, Ying; Han, Yu; Chen, Shizhu; Liu, Jingjie; Wang, Dajiang; Huang, Yifei

doi:10.1016/j.apsb.2021.10.009

Cited by 22 publications

(13 citation statements)

References 43 publications

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“…Another study was conducted on new NPs assembled by liposomes and indocyanine green (ICG) for the treatment of retinoblastoma, which overcame the ICG's easy selfaggregation and instability, and also enabled image-guided photothermal therapy [131].…”

Section: Stargardt Diseasementioning

confidence: 99%

Exploration: Nanoparticles in the Diagnosis and Treatment of Retinal Diseases

Wang

Xie

Chen

et al. 2023

Journal of Nanomaterials

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In recent years, research on nanoparticles (NPs) has brought a new phase in the development of medicine. The term “NPs” refers to nanoscale particles, typically between 10 and 1,000 nm in size, that are within the range of cellular and molecular structures. Compared with traditional ophthalmic drugs, NPs can carry drugs to overcome obstacles, target drug delivery, prolong drug release, reduce drug toxicity, and can be used in gene therapy. After a brief introduction to the classification of NPs, we will focus on the potential applications of different NPs in the diagnosis and treatment of different retinal diseases and introduce innovative methods derived from NPs.

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Section: Stargardt Diseasementioning

confidence: 99%

Exploration: Nanoparticles in the Diagnosis and Treatment of Retinal Diseases

Wang

Xie

Chen

et al. 2023

Journal of Nanomaterials

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“…More preclinical and clinical studies suggested that ICG-based photoresponsive liposomes − may be an alternative to chemotherapy. As a piece of evidence, Yorozu and colleagues reported a classic case of ICG photoresponsive liposomes used in the treatment of human advanced cancer.…”

Section: Photoresponsive Liposomes Based On Organic Photosensitizersmentioning

confidence: 99%

Recent Development of Photoresponsive Liposomes Based on Organic Photosensitizers, Au Nanoparticles, and Azobenzene Derivatives for Nanomedicine

Pan

et al. 2022

ACS Appl. Nano Mater.

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Photoresponsive liposomes are controlled-release liposomes modified by photoresponsive materials. They use light with high spatial and temporal precision as a means of regulation. After excitation by light at appropriate wavelengths, photoresponsive liposomes can influence the permeability of phospholipid bilayers through the photothermal or photoisomerization effect of photoresponsive materials. The photothermal effect causes the phospholipid layer to become dispersed by local heating, and the photoisomerization effect modulates the release behavior by establishing permeation channels on the phospholipid layer through changes in the dipole moments of azobenzene derivatives. Currently, photoresponsive liposomes are widely used as a cutting-edge strategy for nanomedicine. In this paper, three types of photoresponsive liposomes based on organic photosensitizers, Au nanoparticles, and azobenzene derivatives with abundant research reports were introduced based on the differences in the photoresponse principles and forms of different photoresponsive materials. This review aims to reflect the differences in the structures, properties, photoresponsive materials, and principles of action of different photoresponsive liposomes. Moreover, this work outlines the current status of their application in the field of nanomedicine.

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“…In another approach, ICG was assembled in liposomes for photothermal therapy of retinoblastoma, and the liposomes were able to overcome limitations usually encountered with ICG delivery, e.g., quenching, aggregation, and instability. Moreover, the liposomes could achieve specific tumor tissue targeting and penetration in vitro and in vivo and efficient accumulation in solid tumors which enhanced the efficacy of tumor photothermal therapy [136].…”

Section: Photothermal Reactionsmentioning

confidence: 99%

Light-responsive biomaterials for ocular drug delivery

Abdelmohsen

Copeland

Hardy

2022

Drug Deliv. and Transl. Res.

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Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmology make light-responsive delivery of drugs feasible. Importantly, light can be applied in a non-invasive fashion; therefore, light-triggered drug delivery systems have great potential for clinical impact. This review will examine various types of light-responsive polymers and the chemistry that underpins their application as ophthalmic drug delivery systems. Graphical abstract

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Liposome-based multifunctional nanoplatform as effective therapeutics for the treatment of retinoblastoma

Cited by 22 publications

References 43 publications

Exploration: Nanoparticles in the Diagnosis and Treatment of Retinal Diseases

Exploration: Nanoparticles in the Diagnosis and Treatment of Retinal Diseases

Recent Development of Photoresponsive Liposomes Based on Organic Photosensitizers, Au Nanoparticles, and Azobenzene Derivatives for Nanomedicine

Light-responsive biomaterials for ocular drug delivery

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