“…4) with considerable potential for delivery of therapeutic agents due to several features: biodegradability, biocompatibility, simplicity, scaled-up production, low inherent toxicity, weak immunogenicity, versatility in structure and in physicochemical properties (lipid composition, size and surface charge) and ability to undergo surface engineering towards conjugation of polymers and targeting ligands (Immordino et al, 2006;Hofheinz et al, 2005;Cattel et al, 2003). Due to those specific attributes, liposomes have the ability to modulate in vivo behavior (pharmacokinetics and biodistribution profile) and/or solubility properties of drugs and to protect them from premature degradation or inactivation after intravenous administration (Fenske et al, 2008;Immordino et al, 2006;Drummond et al, 1999;Allen, 1998). In general, when a drug is encapsulated within a carrier, such as liposome (Fig.…”