Liposclerosing myxofibrous tumor: a rare tumor of proximal femur

Beytemür, Ozan; Tetikkurt, Seza; Albay, Cem; Kavşut, Gonca; Güleç, Akif

doi:10.5606/ehc.2017.48394

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…Therefore, the authors of this paper believe that LSMFT is closely related to fibrous dysplasia (12). But some argue that the histological structure of LSMFT exceeds the range of histological structures currently reported for fibrous dysplasia and the tumor should therefore be treated as a distinct lesion (4,7,13,14). Several authors even suggest that LSMFT should be classified as a true clinicopathological entity and included in textbooks of orthopedic pathology (14).…”

Section: Discussionmentioning

confidence: 99%

Liposclerosing myxofibrous tumor of the distal femur: A case report

Zhang

et al. 2023

Front. Surg.

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IntroductionLiposclerosing myxofibrous tumor (LSMFT) is a rare benign fibro-osseous tumor that most frequently occurs in the proximal femur. The reported literature shows that the proximal femur, ilium, tibia, humerus, rib, and skull have occurred, but so far, the female distal femur has not been characterized in detail. This, we think, is the first single comprehensive case report of the female distal femur. To prevent misdiagnosis and overtreatment of this illness, it is critical for us to continue strengthening our knowledge of it and to add it to the differential diagnosis of the space-occupying lesion of the female distal femur.Case summaryTwo months ago, a 55-year-old female patient was found to have a space-occupying lesion of the left distal femur and the pain symptom was aggravated. She underwent thorough curettage and bone grafting without additional treatment to relieve the current symptoms and determine the nature of the lesion in our hospital. The intraoperative specimens were submitted to the pathology laboratory for analysis, and the result was reported as LSMFT. And six months after the operation, the patient returned to our hospital for another x-ray examination and we found that she had recovered well without any signs of recurrence. The patient self-reported that she had now resumed her daily life without any uncomfortable symptoms.ConclusionThe incidence of LSMFT itself is relatively low, and the occurrence of the distal femur is even rarer. However, it is recommended to add LSMFT into the differential diagnosis of the occupying lesions of the distal femur. Once the diagnosis is made, thorough curettage and bone grafting without additional special treatment can achieve better postoperative outcomes. The patient gave her agreement after learning that information about the case will be submitted for publication.

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Section: Discussionmentioning

confidence: 99%

Liposclerosing myxofibrous tumor of the distal femur: A case report

Zhang

et al. 2023

Front. Surg.

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“…1 It is a benign fibro-osseous lesion, which has myxoid areas, osteoclastic activity, bone trabeculae similar to fibrous dysplasia, fat necrosis, ischaemic ossification and rarely cartilage components. 2 It is found to occur most commonly in the fourth decade of life and proximal femur has been reported as the most common location. 3 A few cases of malignant transformation of the lesion have been documented, and hence, it warrants close observation and follow-up.…”

Section: Descriptionmentioning

confidence: 99%

Liposclerosing myxofibrous tumour

Pai

Kumar

2021

BMJ Case Rep

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“…4 De los casos, 85% se localizan en el fémur proximal, sobre todo en la región intertrocantérea, aunque este asiento no es exclusivo. 2 Existen casos descritos en ilion, húmero, tibia, cráneo, costilla y acetábulo. [5][6][7][8][9] Desde el punto de vista radiológico se trata de una lesión lítica, con patrón geográfico, de margen bien definido y por lo regular esclerótico; con frecuencia con mineralización en su interior o un cierto grado de expansión en el contorno.…”

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Mixofibroma lipoesclerosante de fémur proximal: controversias diagnósticas y terapéuticas. A propósito de 3 casos clínicos

Romero¹,

Montijano²,

Rubio³

et al. 2022

Ortho-Tips

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Introducción: El mixofibroma lipoesclerosante (MFLE) es un tumor benigno fibro-óseo poco frecuente con características clínico-radiológicas distintivas, si bien de diagnóstico y tratamiento controvertidos. Material y métodos: Se describen tres casos clínicos, dos mujeres y un hombre, con una edad media de 46 años, diagnosticados de MFLE. Se presentan los hallazgos de las pruebas complementarias de imagen y el tratamiento realizado: observación en dos pacientes y tratamiento quirúrgico (curetaje, relleno con homoinjerto óseo y fijación quirúrgica) en el tercero. Resultados: Los dos primeros pacientes, después de 10 y tres años de seguimiento, respectivamente, mantienen las mismas molestias y ausencia de progresión de la lesión. La paciente intervenida, con dos años de evolución, refiere dolor de menos intensidad al original sin signos de recidiva tumoral. Conclusiones: El diagnóstico de MFLE puede asumirse por datos clínicos y de imagen sin necesidad de biopsia. En ausencia de signos que hagan sospechar malignidad está justificada la vigilancia estrecha, limitándose la indicación quirúrgica a los casos sintomáticos y/o con riesgo de fractura patológica.

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Liposclerosing myxofibrous tumor: a rare tumor of proximal femur

Cited by 3 publications

References 8 publications

Liposclerosing myxofibrous tumor of the distal femur: A case report

Liposclerosing myxofibrous tumor of the distal femur: A case report

Liposclerosing myxofibrous tumour

Mixofibroma lipoesclerosante de fémur proximal: controversias diagnósticas y terapéuticas. A propósito de 3 casos clínicos

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