Lipoprotein lipase activity in human heart

Schnatz, J. David; Ormsby, John W.; Williams, Robert H.

doi:10.1152/ajplegacy.1963.205.2.401

Cited by 14 publications

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“…The lipase level in blood serum is a diagnostic indicator for conditions such as acute pancreatitis and pancreatic injury [143]. Lipase activity/level determination is also important in the diagnosis of heart ailments [144]. …”

Section: Applicationsmentioning

confidence: 99%

Organic Solvent Tolerant Lipases and Applications

Sharma

Kanwar

2014

The Scientific World Journal

216

161

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Lipases are a group of enzymes naturally endowed with the property of performing reactions in aqueous as well as organic solvents. The esterification reactions using lipase(s) could be performed in water-restricted organic media as organic solvent(s) not only improve(s) the solubility of substrate and reactant in reaction mixture but also permit(s) the reaction in the reverse direction, and often it is easy to recover the product in organic phase in two-phase equilibrium systems. The use of organic solvent tolerant lipase in organic media has exhibited many advantages: increased activity and stability, regiospecificity and stereoselectivity, higher solubility of substrate, ease of products recovery, and ability to shift the reaction equilibrium toward synthetic direction. Therefore the search for organic solvent tolerant enzymes has been an extensive area of research. A variety of fatty acid esters are now being produced commercially using immobilized lipase in nonaqueous solvents. This review describes the organic tolerance and industrial application of lipases. The main emphasis is to study the nature of organic solvent tolerant lipases. Also, the potential industrial applications that make lipases the biocatalysts of choice for the present and future have been presented.

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Section: Applicationsmentioning

confidence: 99%

Organic Solvent Tolerant Lipases and Applications

Sharma

Kanwar

2014

The Scientific World Journal

216

161

View full text Add to dashboard Cite

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“…The lipase level in blood serum is a diagnostic indicator for conditions such as acute pancreatitis and pancreatic injury [59,66]. Lipase activity determination is also significant in the diagnosis of heart ailments [67]. Lipases may be immobilized onto pH/oxygen electrodes in combination with glucose oxidase, and these function as lipid biosensors and used in triglycerides and blood cholesterol determinations [68].…”

Section: In Medical Applicationsmentioning

confidence: 99%

Overview of Fungal Lipase: A Review

Singh

Mukhopadhyay

2011

Appl Biochem Biotechnol

343

211

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Lipases (triacylglycerolacyl hydrolases, EC3.1.1.3) are class of enzymes which catalyze the hydrolysis of long-chain triglycerides. In this review paper, an overview regarding the fungal lipase production, purification, and application is discussed. The review describes various industrial applications of lipase in pulp and paper, food, detergent, and textile industries. Some important lipase-producing fungal genera include Aspergillus, Penicillium, Rhizopus, Candida, etc. Current fermentation process techniques such as batch, fed-batch, and continuous mode of lipase production in submerged and solid-state fermentations are discussed in details. The purification of lipase by hydrophobic interaction chromatography is also discussed. The development of mathematical models applied to lipase production is discussed with special emphasis on lipase engineering.

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“…The lipase level in blood serum is a diagnostic indicator for conditions such as acute pancreatitis and pancreatic injury (65,66) (the lipase assay is more sensitive than amylase estimation). Lipase activity/level determination is also important in the diagnosis of heart ailments (67).…”

Section: Hydrolysismentioning

confidence: 99%

Applications of lipase

Gandhi

1997

J Americ Oil Chem Soc

337

170

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Lipases are endowed with a substrate specificity that surpasses that of any other known enzyme. This confers on these enzymes an application potential that is literally boundless. Lipases can be employed in the production of pharmaceuticals, cosmetics, leather, detergents, foods, perfumery, medical diagnostics, and other organic synthetic materials. This review attempts to present a comprehensive discussion on the present status of this unique group of enzymes in industry, as well as the actual potential. It represents an endeavor to provide a sincere answer to the question, "What can be done with this enzyme?" as well as, "Can lipase be utilized for this purpose?" It is intended that the manuscript will cover or at least mention all known applications, based on the exploitation of a particular type of reaction catalyzed by lipases. An attempt will be made to cover as large a number of references as possible, so as to further underline the importance and significance of lipase action for industry. JAOCS 74, 621-634 (1997).

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Lipoprotein lipase activity in human heart

Cited by 14 publications

References 0 publications

Organic Solvent Tolerant Lipases and Applications

Organic Solvent Tolerant Lipases and Applications

Overview of Fungal Lipase: A Review

Applications of lipase

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