Lipoprotein(a) as a risk factor for cardiovascular diseases - focus on ischemic stroke (a position paper)
Ia. B. Skiba,
A. Yu. Polushin,
E. S. Saganova
et al.
Abstract:High lipoprotein(a) (LP(a)) level contributes as an independent risk factor to the development of cardiovascular diseases of atherosclerotic origin. The article contains data on the structural features of this particle, the genetic determination of its metabolism and content in blood plasma, and the pathogenic mechanisms of its proatherogenic, proinflammatory and prothrombotic effects. The authors analyzed epidemiological data on the frequency of elevated LP(a) levels in different population groups and its ass… Show more
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