Lipophilic neutral iridium(III) complexes for phosphorescence imaging of lipid droplets and potential photodynamic therapy

Near-infrared AIE-active phosphorescent iridium(iii) complex for mitochondria-targeted photodynamic therapy

“…12 Thanks to their longlived triplet metal-ligand charge transition ( 3 MLCT) excited states, they have a strong ability to generate singlet oxygen even under hypoxic conditions. 13 Phosphorescent cyclometalated Ir(III) complexes with octahedral configuration are easy to be taken up by cells, and after structural modification or ligand modification, they have very good organelle localization properties and can target different organelles, mainly including nucleus, [14][15][16] mitochondria, [17][18][19] lysosomes, [20][21][22] lipid droplets, [23][24][25] and the endoplasmic reticulum (ER). [26][27][28] Moreover, the integrated utilization of the rich photophysical properties and anticancer efficacy of cyclometalated Ir(III) com-plexes is helpful to study their localization in cells and anticancer mechanism, so as to develop anticancer drugs that combine diagnosis and treatment.…”

Stable lignin-based afterglow materials with ultralong phosphorescence lifetimes in solid-state and aqueous solution

“…Pan et al have prepared iridium( iii ) complexes with long-lived phosphorescence from iridium chloride hydrate. 4 Li et al have reported Cs 4 PbBr 6 single crystals with ultralong phosphorescence under the excitation of X-rays. 5 However, realizing phosphorescence at room temperature with these materials is difficult, due to the spin prohibition of triplet exciton transitions.…”

A narrowband red-emitting asymmetric iridium(iii) complex featuring B- and N-embedded π-conjugation units: structure, photophysics and OLED application

“…Phosphorescent metal iridium(III) complexes, as excellent room temperature phosphorescent materials, are widely used in organic light-emitting diodes (OLEDs), [1][2][3][4][5][6][7][8][9][10] chemical sensing, [11][12][13][14][15] biological imaging, [16][17][18][19][20] photocatalysts for organic reactions, [21][22][23][24] etc. Especially for phosphorescent OLEDs which can be used in flat-panel displays and lighting sources, metal iridium complexes have more advantages, including a stable octahedral coordination structure, a suitable luminescence lifetime, an adjustable luminescence color, high luminescence efficiency and exciton utilization.…”