Lipomatous differentiation in a medulloblastoma

Chimelli, Leila; Hahn, M.; Budka, Herbert

doi:10.1007/bf00293470

Cited by 51 publications

(40 citation statements)

References 11 publications

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“…1,[4][5][6]8,10,12 The growth fractions have ranged from less than 1 to 6%, with a mean value of 2.5%. 1,[4][5][6]8,10,12 The growth fractions have ranged from less than 1 to 6%, with a mean value of 2.5%.…”

Section: Discussionmentioning

confidence: 98%

Cerebellar liponeurocytoma

Jackson¹,

Regine²,

Wilson³

et al. 2001

Journal of Neurosurgery

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Cerebellar liponeurocytoma is a rare tumor of the posterior fossa that has many morphological similarities to medulloblastoma and neurocytoma. Recently the World Health Organization working group for classification of central nervous system neoplasms adopted the term "cerebellar liponeurocytoma" to provide a unified nomenclature for a tumor variously labeled in the literature as lipomatous medulloblastoma, lipidized medulloblastoma, medullocytoma. neurolipocytoma, lipomatous glioneurocytoma, and lipidized mature neuroectodermal tumor of the cerebellum. The rarity of this tumor and paucity of pertinent information regarding its biological potential and natural history have resulted in the application of various treatment modalities. It is suggested in the available literature that these lesions have a much more favorable prognosis than typical medulloblastomas, and that adjuvant therapy for liponeurocytoma need not be as extensive as that administered for medulloblastomas.

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Section: Discussionmentioning

confidence: 98%

Cerebellar liponeurocytoma

Jackson¹,

Regine²,

Wilson³

et al. 2001

Journal of Neurosurgery

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“…The other terms included medullocytoma and lipomatous glioneurocytoma [7,9,30] Importantly, the retrospective analysis of over 350 pediatric medulloblastomas [30] failed to identify any tumor with adipocytes. In 1998 [10] one case was called a lipidized mature neuroectodermal tumor of the cerebellum.…”

Section: Discussionmentioning

confidence: 99%

Cerebellar liponeurocytoma with atypical histological features – a rare example of a glioneuronal tumor

Hermann¹,

Woźnica²,

Kloc³

et al. 2017

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“…The pathological features resembling medulloblastoma in addition to lipidized cells originally resulted in a variety of names, including 'lipomatous medulloblastoma' [2][3][4] , 'lipidized medulloblastoma' 5,6 , 'medullocytoma' 6 , 'neurolipocytoma' 7 , and 'lipomatous glioneurocytoma' 8 . However, due to the tumor's different prognosis, epidemiology, and clinical presentation, the World Health Organization in 2000 defined cerebellar liponeurocytoma as a distinct lesion from medulloblastoma.…”

Section: Discussionmentioning

confidence: 99%

Multifocal Cerebellar Liponeurocytoma

Pelz¹,

Khezri

Mainprize

et al. 2013

Can. J. Neurol. Sci.

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A 54-year-old female presented with a two year history of progressive headaches and upper neck pain. The headaches were worse with coughing and bending. Neurological examination was unremarkable including a normal cranial nerve examination. There was no papilloedema. A computed tomogram (CT) demonstrated a midline, posterior fossa, partly fatty, partly solid mass ( Figure 1). Magnetic resonance imaging (MRI) demonstrated a mixed fatty, solid mass arising from the fourth ventricle and extending downward below the foramen magnum to the C1 level ( Figure 2). The solid portions demonstrated enhancement. In addition, in the lateral right cerebellar hemisphere, there was a second, separate, solid, enhancing mass without any connection to the larger central lesion. A subtotal resection of the tumor was achieved through a suboccipital craniectomy.The tumor had a biphasic pathologic appearance, comprised of mature adipose tissue and densely cellular neurocytic neoplasm. In some areas, these two morphologies were juxtaposed ( Figure 3A) and in other areas they were

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Lipomatous differentiation in a medulloblastoma

Cited by 51 publications

References 11 publications

Cerebellar liponeurocytoma

Cerebellar liponeurocytoma

Cerebellar liponeurocytoma with atypical histological features – a rare example of a glioneuronal tumor

Multifocal Cerebellar Liponeurocytoma

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