Lipomata of the inferior vena cava: A normal variant?

Perry, J.N.; Williams, M.; Dubbins, Paul A.; Farrow, Richard

doi:10.1016/s0009-9260(05)81802-1

Cited by 23 publications

(21 citation statements)

References 4 publications

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“…Intravascular lipoma is a very rare condition with unclear physiopathology mechanism, which includes both individual tissue sensibility and different number of cellular receptors to corticosteroids 3 . Although the venous media layer has few adipocytes 5 , intravenous lipoma may developed either from the vein wall (intraluminal origin) or by invagination of adjacent adipose tissue (extraluminal origin) 5,6,12,13 . Differential diagnosis includes both benign (hemangioma, thombosis, leiomyoma,) and malignant (leiomyosarcoma, angiosarcoma) conditions 6,9,13,14 .…”

Section: Discussionmentioning

confidence: 99%

“…Although the venous media layer has few adipocytes 5 , intravenous lipoma may developed either from the vein wall (intraluminal origin) or by invagination of adjacent adipose tissue (extraluminal origin) 5,6,12,13 . Differential diagnosis includes both benign (hemangioma, thombosis, leiomyoma,) and malignant (leiomyosarcoma, angiosarcoma) conditions 6,9,13,14 . A possible concern could be about the absence of surgical findings; however, a densitometric study of CT scans well demonstrated an homogenous mass with hypo attenuation and characteristics of normal fatty tissue 4 .…”

Section: Discussionmentioning

confidence: 99%

“…A possible concern could be about the absence of surgical findings; however, a densitometric study of CT scans well demonstrated an homogenous mass with hypo attenuation and characteristics of normal fatty tissue 4 . There was no enhancement after injection of contrast [12][13][14] , and the volume of the mass did not change during four years of control by comparative imaging studies. Diagnosis of intravenous lipoma, and lipomas from diverse locations have been similarly characterized with base on typical images of CT and magnetic resonance studies 4,[6][7][8][9][12][13][14] .…”

Section: Discussionmentioning

confidence: 99%

“…There was no enhancement after injection of contrast [12][13][14] , and the volume of the mass did not change during four years of control by comparative imaging studies. Diagnosis of intravenous lipoma, and lipomas from diverse locations have been similarly characterized with base on typical images of CT and magnetic resonance studies 4,[6][7][8][9][12][13][14] . Moreover, the lack of histopathology data in the case of this patient seems justified 6,9,12 , and does not differ of three of the case studies that were previously published 6,8,9 .…”

Section: Discussionmentioning

confidence: 99%

“…Main factors involved in the genesis of corticoid-induced epidural lipomas include hypothyroidism, and Paget disease of bone 3 . Otherwise, intravascular lipomas are related to liver cirrhosis, hepatic tumors, renal angiomyolipoma, direct vessel injury and obesity 12,13 . The probable causal relationship between chronic use of corticoster-oids and the origin of lipoma in the patient here described also differs from the eight similar cases of lipomas found within the superior vena cava, and the brachiocephalic or the subclavian veins [4][5][6][7][8][9][10][11] .…”

Section: Discussionmentioning

confidence: 99%

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Intravenous lipoma and pulmonary sarcoidosis treated with prednisone

Santos

Pitol

et al. 2012

Anales Sis San Navarra

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Corticosteroid-induced lipomatosis is not a rare condition, but lipoma in the central veins has scarcely been described. According to the databases consulted, this is the first report of a lipoma within the central veins coexistent with long-term use of corticosteroid. It involved a 47-year-old male under treatment for pulmonary sarcoidosis with prednisone. Computerized tomography of the thorax was performed and incidentally the images showed a mass within the central veins with the characteristics of lipoma. He was asymptomatic and refused surgical procedures. The intraluminal lipoma originated in the right brachiocephalic and subclavian veins. Control tomography showed a slow development of this lipoma, without obstructive effects or malignant features. Oral prednisone was changed for methotrexate. The patient is asymptomatic and under longstanding out-patient surveillance. Corticosteroid treatments for sarcoidosis can play a role in the development of intravascular lipoma, but this association is not well defined. Case reports could contribute to clarifying whether this relationship is causal or merely casual. REsUMEnLa lipomatosis inducida por glucocorticoides no es una entidad rara, pero hay pocos casos descritos de lipoma en las venas centrales. Según la bibliografía, éste es el primer trabajo de un paciente con un lipoma en las venas centrales coexistente con el uso de glucocorticoide a largo plazo. Se trata de un hombre de 47 años, en tratamiento de sarcoidosis pulmonar con prednisona. Se realizó tomografía computarizada de tórax e incidentalmente, las imágenes mostraron una masa en las venas centrales, con características de lipoma. El paciente estaba asintomático y se negó a la realización del procedimiento quirúrgico. Este lipoma intraluminal se originó en la vena braquiocefálica y subclavia derecha. El estudio tomográfico demostró un desarrollo lento del lipoma, sin efectos obstructivos ni características malignas. La prednisona oral se cambió por metotrexate. El paciente permanece asintomático, realizando un seguimiento ambulatorio. Los tratamientos con glucocorticoides para sarcoidosis pueden desempeñar un papel importante en el desarrollo de lipomas intravasculares, pero esta asociación no está bien definida. Se desconoce si la relación de esta asociación es causal o meramente casual.Palabras clave. Glucocorticoides. Lipoma intravascular. Sarcoidosis. Vena braquiocefálica. Vena subclavia.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Intravenous lipoma and pulmonary sarcoidosis treated with prednisone

Santos

Pitol

et al. 2012

Anales Sis San Navarra

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“Lipoma” of the inferior vena cava is actually a pericaval fat collection

Katz¹,

Goffner²

2001

J of Clinical Ultrasound

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Sonographic appearance of lipoma of the inferior vena cava

Chou

Chiou

Tiu

et al. 2001

J of Clinical Ultrasound

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Lipomas of the major central veins are rare, and their sonographic features have rarely been reported. We report a case in which a lipoma of the inferior vena cava (IVC) was incidentally identified during liver sonography in a 68-year-old man. Sonography of the upper abdomen revealed coarsening of the liver echotexture, with a relatively small liver and atrophy of the right hepatic lobe. A 2-cm hypoechoic hepatic nodule was visualized in segment IV. Sonography also showed a 2.2- x 1.8-cm, highly echogenic, homogeneous nodule in the hepatic segment of the IVC at its junction with the right atrium. The lumen of the IVC was partially occluded. The CT and MRI appearances of the IVC lesion were consistent with a lipoma, which was not treated because there was no clinical evidence of obstruction. Histopathologic analysis following a sonographically guided biopsy of the liver nodule revealed hepatocellular carcinoma, which was treated by percutaneous ethanol injection.

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Lipomata of the inferior vena cava: A normal variant?

Cited by 23 publications

References 4 publications

Intravenous lipoma and pulmonary sarcoidosis treated with prednisone

Intravenous lipoma and pulmonary sarcoidosis treated with prednisone

“Lipoma” of the inferior vena cava is actually a pericaval fat collection

Sonographic appearance of lipoma of the inferior vena cava

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