Lipoma of the lip

Turner, H. Dixon

doi:10.1016/0030-4220(56)90026-3

Cited by 17 publications

(2 citation statements)

References 2 publications

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“…19 Lipomas tend to grow in areas that receive continuous stretching, but the exact mechanism remains unknown. 20,21 All of the lipomas in this study were observed in regions, such as the mouth, neck, shoulder/axilla, scapular, or lumbar, which received continuous stretching stimuli. Therefore, these results support the hypothesis that lipomas might grow in the area where the movement of the bones, such as the mandible, cervical spine, clavicle, rib, scapula, and ilium, is similar to that of the joints, and could also provide the moving stimuli to the subcutaneous adipofascial tissue.…”

Section: Discussionmentioning

confidence: 91%

The Growth Factors of Subcutaneous Benign Lipoma: Consideration from Anatomical Position of Occurrence

Nakao

Onishi

Kiyama

et al. 2022

Plastic and Reconstructive Surgery - Global Open

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Background: Subcutaneous lipomas are the most common benign soft-tissue tumors. Theoretically, adipocyte sites could be the primary foci; however, lipomas are likely located in the occipital, neck, shoulder, torso, and thigh areas. To date, no study has reported the anatomical relationship between these subcutaneous structures and lipomas. Therefore, we aimed to investigate the anatomical locations of lipomas and considered their growth factors. In addition, we discussed the mechanism of fat amplification to improve the success of fat grafting. Methods: In the present study, lipomas measuring more than 5 cm in diameter from patients hospitalized between 2017 and 2021 were retrospectively examined using preoperative computed tomography and magnetic resonance imaging as well as clinical records with intraoperative pictures. Results: In total, 22 lipomas of 22 patients were examined. All lesions (100%) were accompanied by neurovascular perforators. Nineteen lesions (86%) were located deep in the superficial fascia, where it was clearly defined. Moreover, all lesions were located at the mobile adipofascial layer adjacent to an anchored fixed or less mobile structure. Conclusions: Lipoma growth might require neurovascular perforators that supply both blood flow and continuous stretching stimuli. The mobile adipofascial layer with bones adjacent to a fixed or less mobile area might also be necessary to grow lipomas. If these findings can be used as clues to elucidate the mechanism of fat amplification in the future, it may lead to an improvement in the survival rate of fat grafts.

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Section: Discussionmentioning

confidence: 91%

The Growth Factors of Subcutaneous Benign Lipoma: Consideration from Anatomical Position of Occurrence

Nakao

Onishi

Kiyama

et al. 2022

Plastic and Reconstructive Surgery - Global Open

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“…[ 27 , 28 ] Notably, the post-traumatic lipoma of the lower lip reported by Turner et al in 1956 highlighted trauma as a possible inducer of lipoma. [ 29 ] Tewfik et al documented a case of subcutaneous lipoma following a parietal fracture, outlining the potential mechanisms for posttraumatic lipoma development: Disruption of the fibrous septum and anchoring connections between the skin and deep fascia, leading to adipose tissue proliferation; local inflammation secondary to trauma, which may promote preadipocyte differentiation and maturation. [ 12 ] Furthermore, Koh et al identified the use of tamoxifen and subcutaneous injections of phosphatidylcholine and deoxycholate as potential risk factors for lipoma formation.…”

Section: Discussionmentioning

confidence: 99%

Fibrolipoma of the lower lip: A case report and review of the literature

Wang,

Yu,

Gao

et al. 2024

Medicine

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Background: Fibrolipoma of the lower lip is an uncommon condition with limited documentation in the literature. This paper provides updated insights into oral and maxillofacial lipomas through a detailed case report and comprehensive literature review, discussing clinical features, pathogenesis, diagnostic approaches, histopathology, and therapeutic strategies. Case presentation: A 54-year-old female presented with a painless, enlarging mass on the inner aspect of her right lower lip, first noticed 2 years prior. The mass, now the size of a peanut, interfered with her eating and speech. Physical examination revealed a 2.0 × 2.5 × 1.0 cm mass beneath the mucous membrane of the right lower lip. It was firm, well-demarcated, and mobile. Surgical excision was performed, and histopathological analysis confirmed the diagnosis of a lower lip fibrolipoma. The lesion was successfully removed without recurrence. Conclusion: Lipomas in the oral and maxillofacial regions are rare, slow-growing benign tumors, particularly within the lips. Although their diagnosis is straightforward based on clinical presentation, histopathological confirmation is essential. Surgical resection remains the treatment of choice, with excellent prognostic outcomes.

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Mundhöhle, Mundspeicheldrüsen, Tonsillen und Rachen

Seifert

1966

Mundhöhle, Mundspeicheldrüsen, Tonsillen Und Rachen. Zähne Und Zahnhalteapparat

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Lipoma of the lip

Cited by 17 publications

References 2 publications

The Growth Factors of Subcutaneous Benign Lipoma: Consideration from Anatomical Position of Occurrence

The Growth Factors of Subcutaneous Benign Lipoma: Consideration from Anatomical Position of Occurrence

Fibrolipoma of the lower lip: A case report and review of the literature

Mundhöhle, Mundspeicheldrüsen, Tonsillen und Rachen

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