Lipoma of the Corpus Callosum

Abstract

The occurrence of lipomas within the central nervous system is sufficiently uncommon that most cases have stimulated considerable attention. These lesions have been encountered both in the spinal canal and within the cranium. Ehni and Love1 have reviewed the literature on intraspinal lesions and present a detailed discussion of the problem. They include data on 29 cases of intradural and 20 cases of extradural lipomas. Lipomas of the brain are somewhat more numerous, and about 110 cases have been reported. These have occurred in the following areas, in this order of frequency: the corpus callosum, the ventral aspect of the diencephalic structures, the choroid plexus of the lateral ventricles, and the dorsal aspect of the midbrain. Except for the lesions in the corpus callosum, these tumors are ordinarily of little importance and were frequently encountered incidentally at autopsy. In the corpus callosum, however, lipomas were frequently sizable and were often associated with defects in the development of the corpus callosum. A good review of the subject of lipomas of the corpus callosum was contrib¬ uted in 1946 by List and associates.2 They recorded data on 30 cases from the literature, including 2 of their own. Our purpose is to compile information on additional cases re¬ ported since then and to report in detail a case with several unusual features recently

Parietal Lipomeningocele-Case Report-

“…14) In general, most patients with intracranial lipoma are asymptomatic, but epilepsy occurs in 30-50%. 4,5) Five of the 11 patients with extracranial and intracranial lipoma suffered epilepsy, 8,11,13,15,16) which is quite similar to the frequency observed in cases of intracranial lipoma. 4,5) The intracranial lipomas commonly show little neoplastic proliferation, but are too difficult to extirpate due to their vascularity and very strong attachment to the surrounding structures.…”

“…5,20) Extracranial extension of intracranial lipoma via the cranium bifidum has been reported in 11 cases including our present case (Table 1). 1,2,8,[10][11][12][13][14][15][16] Table 1 excludes the cases of lipoma included in encephalocele. Subcutaneous swelling was observed since birth in all cases.…”

Lipoma do corpo caloso com extensão extracraniana através de falha óssea frontal

“…Evidenciava ainda estenose do seio sagital superior ao nível da fontanela bregmática, elevação das artérias pericalosas na altura do joelho do corpo caloso e discreto desvio unilateral da artéria cerebral anterior direita (Fig 3) Segundo List e col. 10 e Kazner e col. 6 , no sistema nervoso central os lipomas são localizados mais freqüentemente no corpo caloso, sendo também encontrados na região do tuber cinereum, lâmina quadrigêmia, cisterna ambiens, cisterna quiasmática, cisterna da fossa interpeduncular, cisterna silviana, cisterna pontina lateral, cisterna cerebelo-medular, tela coróidea do ventrículo lateral e do III ventrículo. Microscopicamente os lipomas são constituídos de células semelhantes à adipócitos adultos, sem evidências de transformação neoplásica 12 . Seu crescimento é lento e considerado como fazendo parte do crescimento dos tecidos como um todo.…”

“…A manifestação clínica do caso relatado neste estudo foi apenas a ocorrência de uma protuberância frontal, sendo também a forma de apresentação de um dos casos de Zee e col. 20 e do caso descrito por Hayashi e col. 5 . O tratamento cirúrgico do lipoma de corpo caloso ocorreu nos casos relatados por Kinol e col. 8 , Nordin e col. 12 e Kazner e col. 6 , com o óbito dos pacientes dos dois primeiros autores. Kazner e col. não informaram, em seu relato, o resultado cirúrgico e as condições pós-operatórias do paciente.…”

Lipoma of the Corpus callosum: Report of a Case and Review of the Literature

“…[11 ], Nordin et al [ 14], Zettner et al [22], Cooper et al [6] and Nonaka et al [12] reviewed the literature and charted the pertinent clinical features of the cases. We have been able to find 15 cases not previously compiled in these reviews.…”