Lipoid proteinosis of the larynx in siblings: exploring new modalities of treatment

Abstract

Lipoid proteinosis is a rare autosomal recessive disease inheritance with deposition of hyaline-like material at cutaneous and non-cutaneous sites. This is a report of two siblings presenting with typical cutaneous and laryngeal manifestations of lipoid proteinosis since birth who were treated successfully with placental extract.

Lipoid proteinosis: Review of Indian cases

“…Hence, review of 51 cases of LP reported in India from 1969 to 2021 is done along with the present case [ Table 1a – c ]. [ 1 4 5 6 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 ] LP is more reported in patients in the age group of 11-20 (51%). More prevalence of LP is reported in males (70.6%).…”

“…On review of oral manifestations, 42 cases were found as shown in Table 1c . [ 1 4 5 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 25 26 27 28 29 30 31 32 33 34 35 37 38 39 42 43 44 ] The most common involved site is tongue with typical thick woody appearance followed by restricted tongue movements. In the present case, also similar findings were present.…”