Lipodystrophy Severity Does Not Contribute to HAART Nonadherence

Collins, Evan; Burgoyne, Robert W.; Wagner, Cheryl A.; Halman, Mark; Nur, Margaret; Walmsley, Sharon

doi:10.1007/s10461-005-9048-4

Cited by 8 publications

(4 citation statements)

References 16 publications

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“…Self-reported body morphology abnormalities have been scored in several ways, including as binary, categorical, and continuous outcomes. [49][50][51][52][53] Few comparisons have been made between approaches. Categorizing or dichotomizing outcomes can be advantageous for improving interpretability and ease of describing results.…”

Section: Measurement or Scoring Of Lipohypertrophy And Lipoatrophymentioning

confidence: 99%

Associations Between At-Risk Alcohol Use, Substance Use, and Smoking with Lipohypertrophy and Lipoatrophy Among Patients Living with HIV

Noorhasan

Drozd

Grünfeld

et al. 2017

AIDS Research and Human Retroviruses

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We found a high prevalence of lipohypertrophy and lipoatrophy among a nationally distributed cohort of PLWH. While low levels of physical activity were associated with both lipohypertrophy and lipoatrophy, associations with substance use and other clinical characteristics differed between lipohypertrophy and lipoatrophy. These results support the conclusion that lipohypertrophy and lipoatrophy are distinct, and highlight differential associations with specific illicit drug use.

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Section: Measurement or Scoring Of Lipohypertrophy And Lipoatrophymentioning

confidence: 99%

Associations Between At-Risk Alcohol Use, Substance Use, and Smoking with Lipohypertrophy and Lipoatrophy Among Patients Living with HIV

Noorhasan

Drozd

Grünfeld

et al. 2017

AIDS Research and Human Retroviruses

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“…Lipodystrophy is loosely defined as a set of symptoms associated with continued use of Highly Active Retroviral Therapy (HAART), chiefly, fat atrophy of the arms, legs, face, and buttocks, and hypertrophy of fat in the abdomen and neck [4]. Additionally, lipodystrophy has a particularly important role in HAART adherence, as several, although not all reports [8], have identified self-perceived changes in body fat to be related to HAART nonadherence [5,6,9,10]. This potential for non-adherence has striking influences on HIV/AIDS patients, as even occasional non-adherence to treatment is related to deleterious outcomes [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

The Role of Body Image Dissatisfaction and Depression on HAART Adherence in HIV Positive Men: Tests of Mediation Models

Blashill

Wal

2009

AIDS Behav

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The current study examined the role of body image dissatisfaction and depression on HAART adherence in a sample of HIV positive men. Participants were 124 HIV positive gay and bisexual men, who responded to an online survey. Results from moderated mediation models revealed that depression mediated the relationship between body dissatisfaction and HAART non-adherence for men who possessed elevated levels of body dissatisfaction, but not for those men who reported moderate or low levels. Additionally, depression was found to mediate the relationship between body dissatisfaction and HAART non-adherence for men with a self-reported AIDS diagnosis. Results suggest the importance of addressing both body dissatisfaction and depression in men who are living with HIV/AIDS.

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“…Lipodystrophy is characterised by atrophy in the face and upper and lower limbs with fat accumulation in the abdomen and breasts. [ 16 ]…”

Section: Introductionmentioning

confidence: 99%

The Correlation between Anthropometric Variables and Muscular Strength in Patients Coinfected with Leprosy and HIV

Novais,

do Nascimento,

Lopes

et al. 2023

Indian Journal of Dermatology

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Background: Peripheral nerve disease may lead to physical disability because of decreased muscle strength and/or loss of sensitivity in the dermatomes of affected peripheral nerves. Both human immunodeficiency virus (HIV)- and leprosy-affected patients can develop neurological damage; therefore, the coinfection of these diseases presents new challenges to the health care of these patients. Aims and Objective: This study aimed to investigate the motor alterations of patients coinfected with HIV and leprosy and their relationship with clinical and anthropometric characteristics, compared with individuals with isolated diseases. Materials and Methods: In this cross-sectional study, 90 individuals were divided equally into three groups: HIV/acquired immunodeficiency syndrome (AIDS) group, leprosy group and HIV/leprosy group. All individuals underwent an evaluation of muscle strength and upper limb endurance adjusted for the Brazilian standards, a palm print pressure test using a digital dynamometer and anthropometric measurements (weight, height and skin folds). Results: The HIV/leprosy group had the highest mean body mass index, followed by the leprosy group and the HIV/AIDS group. Skinfolds were similar between the groups. Multiple linear regression, adjusted for sex and age, revealed the coinfection of HIV and leprosy as possible contributor to a worse prognosis of muscle function, highlighting the bilateral reduction in the levels of palm print compression strengths compared with isolated diseases (HIV and leprosy). High CD4 count and shorter antiretroviral therapy duration were associated with worse indices of muscle strength, such as gripping and resistance, in coinfected patients. Conclusion: Patients coinfected with HIV and leprosy exhibited greater motor damage than those with isolated diseases. Thus, motor damage may be related to the sum of the neurological manifestations of the two morbidities.

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Lipodystrophy Severity Does Not Contribute to HAART Nonadherence

Cited by 8 publications

References 16 publications

Associations Between At-Risk Alcohol Use, Substance Use, and Smoking with Lipohypertrophy and Lipoatrophy Among Patients Living with HIV

Associations Between At-Risk Alcohol Use, Substance Use, and Smoking with Lipohypertrophy and Lipoatrophy Among Patients Living with HIV

The Role of Body Image Dissatisfaction and Depression on HAART Adherence in HIV Positive Men: Tests of Mediation Models

The Correlation between Anthropometric Variables and Muscular Strength in Patients Coinfected with Leprosy and HIV

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