Lipoatrofia semicircular inducida por presión

Lipoatrophia semicircularis

“…The immunohistochemical study has been done only in one case, showing adipocyte positivity for vimentin and S-100 protein, with few positive histiocytes for CD68 [20].…”

“…Some initial isolated reports were reasonably attributed to local trauma, such as the place of support on a thigh of a bucket for collecting vegetables [8], leaning against desks [9,10], ironing boards, bath's border for washing [11], dresser with mirror [12] or wash bowl while applying make-up [13][14][15], knocking against the edge of the laundry [16], resting against the counter [17], crossing legs beneath the office desk [18], wearing tight jeans, trousers (Figures 1 and 2) or girdle [11,[19][20][21][22], or hold-up stockings [23], frequent use of sports tights [24], elastic bands [25] or hosiery with an elastic component [18], or appearance of lesions some weeks after the introduction of a new chair at office work [26]. Interestingly, in the case described after wearing tight jeans [19], the same authors described identical lesions a year after in a sister of their initial patient, who developed them after wearing the discarded jeans [27].…”

“…When done, these have essentially shown a partial loss of fat, sometimes replaced by new collagen [30], and absence of panniculitis signs. In one case a nearly complete loss of adipose lobules was reported, without signs of inflammation or fibrosis [70]; other cases have shown loosely dispersed fat lobules with medium-sized adipocytes [14], decreased size of adipocytes with intermingled eosinophilic and hyaline material and some histiocyte and lymphocyte infiltration [20,40], mild accentuation of interlobular septa with atrophy and centrilobular fibrosis of some adipocytes without inflammation [23], hemorrhage in the fat tissue compatible with panniculitis [16], complete loss of adipose tissue [34] and involutional adipocytes, numerous capillaries, and a sparse lymphohistiocytic infiltrate with calcification [36].…”

“…Panniculitis shows thickening of interlobular septa with smaller fat lobules. In lipoatrophy interlobular septa and fat lobules are normal and a loss of superficial fat tissue is present [20].…”

Evaluación de Riesgos de Manipulación Repetitiva a Alta Frecuencia Basada en Análisis de Esfuerzos Dinámicos en las Articulaciones sobre Modelos Humanos Digitales

“…La Lipoatrofia Semicircular se presenta principalmente en mujeres, planteándose en estadísticas españolas que llega a predominar en un 85% en el sexo femenino (la proporción de mujeres y hombres es de 6:1). 6 La edad de presentación es principalmente entre 30-40 años. Su causa es desconocida y la evidencia actual orienta a una relación con los lugares de trabajo.…”