Lipids, statins and susceptibility to SARS-CoV-2 and influenza A viruses

Abstract

The extensive and on-going epidemiology studies of the SARS-CoV-2 pandemic have raised interesting observations on statins reducing COVID-19 severity. In this review, literature is analysed to examine how statins affect COVID-19 and influenza A, another pandemic respiratory virus. This information could be useful to prevent or reduce disease severity caused by respiratory viruses.

‘The awesome power of yeast’ in Alzheimer’s disease research

“…It is considered that simvastatin might act on other pathways in addition to that involving cholesterol biosynthesis. One such mechanism that is of high importance is protein prenylation 21 . Importantly, protein prenylation is involved in regulating autophagy, inflammatory responses, oxidative stress and synaptic/cognitive function 22 .…”