Lipids, lipoproteins and other coronary risk factors in Chinese male survivors of myocardial infarction

Woo, Jean; Ho, Suzanne C.; Wong, Sik-Nin; Woo, Kam S.; Tse, C.Y.; Chan, K.K.; Kay, Chiu-San; Mak, W.P.; Cheung, Ka-Ming; Lam, Christopher Wai‐Kei; Donnan, Stuart

doi:10.1016/0167-5273(93)90038-i

Cited by 18 publications

(7 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9 In agreement with the present study, Woo et al also observed higher mean TC, LDL and TG as well as lower mean HDL in AMI patients. 10 Similar results have been also observed by Shirafkan et al who also found higher levels of TC, LDL, VLDL and TG as well as lower levels of HDL in AMI patients. 15 More et al also reported significant increased levels of TC, TG, LDL-C and decreased levels of HDL-C in AMI patients as compared to controls, which are also similar to the findings of our study.…”

Section: Discussionsupporting

confidence: 79%

See 1 more Smart Citation

Lipid profile and its correlation with C-reactive protein in patients of acute myocardial infarction

et al. 2017

View full text Add to dashboard Cite

INTRODUCTIONAcute myocardial infarction (AMI), commonly known as a heart attack, results from the interruption of blood supply to a part of the heart, causing heart cells to die. This is most commonly due to occlusion of a coronary artery following the rupture of a vulnerable atherosclerotic plaque which is an unstable collection of lipids (cholesterol and fatty acids) and white blood cells (especially macrophages) in the wall of an artery. The resulting ischemia (restriction in blood supply) and ensuing oxygen shortage, if left untreated for a sufficient period of time, can cause damage or death (infarction) of heart muscle tissue (i.e. myocardium). 1,2Acute myocardial infarction (AMI) continues to be a major cause of morbidity and mortality worldwide.3,4 It remains a leading cause of death in India and represents an enormous cost to health care system. 5 The mortality rate of MI is approximately 30% and for every 1 in 25 patients who survive the initial hospitalization, dies in the first year after AMI. Indians are four time more prone to AMI as compared to the people of other countries due to a combination of the genetic and lifestyle factors that promote metabolic dysfunction. The risk of ABSTRACT Background: Acute myocardial infarction (AMI) is a significant cause of morbidity and mortality worldwide, which results from occlusion of coronary artery. Dyslipidemia is a major risk factor of AMI. C-reactive protein (CRP) is an acute phase protein, synthesized by hepatocytes in response to cytokines released into circulation by activated leukocytes and has been found to increase after AMI. The objective of the present study is to investigate lipid profile in AMI patients and correlate it with inflammatory marker i.e. CRP. Methods: The present study includes 150 AMI patients and 100 normal healthy individuals as controls. In all the cases and controls, serum lipid profile and inflammatory marker were measured by diagnostic kits supplied by ERBA. Results: The levels of lipid profile and inflammatory marker were significantly altered in the AMI cases compared to controls. We found significantly higher levels of total cholesterol, TG, LDL, VLDL, CRP and lower level of HDL in AMI compared to that of control subjects. We also found strong positive correlation of CRP with total cholesterol, triglyceride, LDL-C and VLDL-C and significant negative correlation with HDL-C in AMI patients. Conclusions: We found alterations in the lipid profile and inflammatory marker in AMI cases; hence, all the people should undergo regular check up including lipid profile evaluation and inflammatory marker such as CRP to decrease the incidence, morbidity and mortality from the disease.

show abstract

Section: Discussionsupporting

confidence: 79%

“…9 Woo et al observed higher mean TC, LDL, and TG as well as lower mean HDL in AMI patients; high HDL was among the protective factors. 10 It is well known fact that early treatment of hyperlipidemia following acute myocardial infarction (AMI) provides potential benefits and reduces the morbidity and mortality of coronary heart disease.…”

Section: Introductionmentioning

confidence: 99%

Lipid profile and its correlation with C-reactive protein in patients of acute myocardial infarction

et al. 2017

View full text Add to dashboard Cite

show abstract

“…3 Previous studies confirm the importance of similar traditional risk factors for coronary artery disease in southern China as in the West. 4,5 But the prevalence of subclinical atherosclerosis in Chinese lupus patients and the related risk factors are remain unknown, which propelled us to start the present study.…”

mentioning

confidence: 99%

Evaluation of Risk Factors That Contribute to High Prevalence of Premature Atherosclerosis in Chinese Premenopausal Systemic Lupus Erythematosus Patients

Zhang¹,

Lu²,

Li³

et al. 2009

JCR: Journal of Clinical Rheumatology

View full text Add to dashboard Cite

show abstract

“…Rather it showed the significant differences in Lp(a) level and HDL-C level among the group. Woo et al, (1993) observed higher mean TC, LDL-C and TG as well as lower mean HDL-C in AMI patients; high HDL-C was among the protective factors. Similarly Kumar et al, 2009 observed significantly higher TC and TG levels and lower HDL-C levels in AMI patients.…”

Section: Discussionmentioning

confidence: 92%

Serum Lipoprotein(A) Concentration is a Better Predictor of Myocardial Infarction than Traditional Lipid Profile and Lipid Ratios

Tamang

Timilsina²,

Singh

et al. 2013

Int J Appl Sci Biotechnol

View full text Add to dashboard Cite

Background-Lipoprotein (a) is a variant form of Low Density Lipoprotein (LDL) which comprises of an LDL like particle in which apo B-100 is firmly linked to apo-a glycoprotein. A large number of genetic and epidemiologic studies have identified Lipoprotein(a) as a risk factor for atherosclerotic diseases such as coronary heart disease and stroke. Based on our knowledge, this is the first study comparing Lipoprotein(a) with lipid profile and lipid ratios in Nepal. Aim & Objective-To compare the serum Lipoprotein(a) and Lipid panel concentrations in myocardial infarction patients and normal healthy control subjects. Materials & Methods-Study was carried out in 45 myocardial infarction patients as cases and 45 healthy subjects as controls. Lipoprotein(a) and Lipid profile tests were measured in serum using HumaStar 600 fully automated analyzer, Human, Germany. Results-Mean serum Lipoprotein(a) concentration in myocardial infarction group was significantly higher as compared to healthy controls. Lipid panel assays were not statistically significant among the groups. Conclusion-Our study revealed that myocardial infarction patients have elevated levels of serum Lipoprotein(a) as compared to healthy subjects. High concentration of serum Lipoprotein(a) is strongly associated with the risk of coronary heart disease.

show abstract

Lipids, lipoproteins and other coronary risk factors in Chinese male survivors of myocardial infarction

Cited by 18 publications

References 25 publications

Lipid profile and its correlation with C-reactive protein in patients of acute myocardial infarction

Lipid profile and its correlation with C-reactive protein in patients of acute myocardial infarction

Evaluation of Risk Factors That Contribute to High Prevalence of Premature Atherosclerosis in Chinese Premenopausal Systemic Lupus Erythematosus Patients

Serum Lipoprotein(A) Concentration is a Better Predictor of Myocardial Infarction than Traditional Lipid Profile and Lipid Ratios

Contact Info

Product

Resources

About