Lipidomics reveals the significance and mechanism of the cellular ceramide metabolism for rotavirus replication
Ran Tao,
Xi Cheng,
Laqiang Gu
et al.
Abstract:As one of the most important causative agents of severe gastroenteritis in children, piglets, and other young animals, species A rotaviruses have adversely impacted both human health and the global swine industry. Vaccines against rotaviruses (RVs) are insufficiently effective, and no specific treatment is available. To understand the relationships between porcine RV (PoRV) infection and enterocytes in terms of the cellular lipid metabolism, we performed an untargeted liquid chromatography mass spectrometry (L… Show more
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