Lipidomics reveals serum lipid metabolism disorders in CTD-induced liver injury
Shan Li,
Xiaotong Duan,
Yixin Zhang
et al.
Abstract:Background
Cantharidin (CTD), the main toxic component of Mylabris, has been extensively used for tumor treatment in recent years. CTD-induced liver toxicity has attracted significant interest in clinic.
Methods
In this study, biochemical parameters and liver pathological changes were analyzed after CTD was administered to mice by gavage. Subsequently, a lipidomic approach was used to investigate serum lipid metabolism disorders, and the mechanism … Show more
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