“Lipidomics”: Mass spectrometric and chemometric analyses of lipids

Wu, Zhuojun; Bagarolo, Giulia Ilaria; Thoröe-Boveleth, Sven; Jankowski, Joachim

doi:10.1016/j.addr.2020.06.009

Cited by 70 publications

(48 citation statements)

References 206 publications

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“…Preanalytical and analytical parameters can affect outcomes of EV lipid analyses and should be reported (Avela & Siren, 2020; Gori et al., 2020; Wu et al., 2020). Protocols for sample preparation, lipid extraction, and separation must be reproducible.…”

Section: Recommendations and Considerationsmentioning

confidence: 99%

“…Therefore, using high‐resolution MS is recommended for analysis of the uEV lipidome (Zullig & Kofeler, 2021). In addition, proper internal standards, normalization and/or labelling are crucially required for precise quantitative lipidomics of uEVs (Avela & Siren, 2020; Glover et al., 2019; Tipthara & Thongboonkerd, 2016; Wu et al., 2020; Zullig & Kofeler, 2021).…”

Section: Recommendations and Considerationsmentioning

confidence: 99%

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Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

Erdbrügger

Blijdorp

Bijnsdorp

et al. 2021

J of Extracellular Vesicle

233

273

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Section: Recommendations and Considerationsmentioning

confidence: 99%

Section: Recommendations and Considerationsmentioning

confidence: 99%

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

Erdbrügger

Blijdorp

Bijnsdorp

et al. 2021

J of Extracellular Vesicle

233

273

View full text Add to dashboard Cite

show abstract

“…The fifth is MALDI imaging [ 54 ], which can be utilized to determine the spatial distribution of lipids in tissue samples; it displays the density of various lipid molecules as a heat map and retains their anatomical structures. This method is hypothesis-free and is expected to achieve a higher throughput lipid analysis [ 55 ].…”

Section: Research Progress Of Lipidomicsmentioning

confidence: 99%

The Function and Mechanism of Lipid Molecules and Their Roles in The Diagnosis and Prognosis of Breast Cancer

et al. 2020

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Lipids are essential components of cell structure and play important roles in signal transduction between cells and body metabolism. With the continuous development and innovation of lipidomics technology, many studies have shown that the relationship between lipids and cancer is steadily increasing, involving cancer occurrence, proliferation, migration, and apoptosis. Breast cancer has seriously affected the safety and quality of life of human beings worldwide and has become a significant public health problem in modern society, with an especially high incidence among women. Therefore, the issue has inspired scientific researchers to study the link between lipids and breast cancer. This article reviews the research progress of lipidomics, the biological characteristics of lipid molecules, and the relationship between some lipids and cancer drug resistance. Furthermore, this work summarizes the lipid molecules related to breast cancer diagnosis and prognosis, and then it clarifies their impact on the occurrence and development of breast cancer The discussion revolves around the current research hotspot long-chain non-coding RNAs (lncRNAs), summarizes and explains their impact on tumor lipid metabolism, and provides more scientific basis for future cancer research studies.

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“…Recently Wu et al. discussed the advantages and limitations of NACE for the analysis and study of lipids [58]. There are many reports on the application of NACE for the analysis of important plants alkaloids (Table 1).…”

Section: Ce For Plant Alkaloids Analysismentioning

confidence: 99%

Recent advances in the analysis of plant alkaloids by capillary electrophoresis and micellar electrokinetic chromatography

Kumar

Malik

Singh

2021

Separation Science Plus

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Plants produce secondary metabolites as a result of a defense mechanism of plants against biotic and abiotic stresses. Alkaloids represent a diverse group of secondary metabolites that contain a basic nitrogen atom. Capillary electrophoresis has many advantages such as short analysis time, little sample consumption, high separation efficiency, and high sensitivity over conventional separation methods. Therefore, capillary electrophoresis has been extensively used for the analysis of alkaloids in plant extracts. In this review, we discuss advances in analytical capillary electrophoresis used for their identification and quantification in plants.

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“Lipidomics”: Mass spectrometric and chemometric analyses of lipids

Cited by 70 publications

References 206 publications

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

The Function and Mechanism of Lipid Molecules and Their Roles in The Diagnosis and Prognosis of Breast Cancer

Recent advances in the analysis of plant alkaloids by capillary electrophoresis and micellar electrokinetic chromatography

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