“…Some researchers have already conducted metabolic profiling on the urine of RC patients using 1H NMR [ 8 , 9 ] and targeted amino acid methods [ 10 ]. Reports on untargeted metabolomics [ 11 ], lipid metabolism [ 12 ], and bile acid metabolism [ 13 ] in animal models of RC are also on the rise. However, there is a relative scarcity of serum-targeted metabolomics, with the focus being primarily on pediatric RC patients [ 14 ].…”