Lipidization as a Tool for Peptide Drug Development
Aneta Myšková,
David Sýkora,
Jaroslav Kuneš
et al.
Abstract:Peptide therapeutics are becoming increasingly important in the quest for effective compounds to treat various difficult-to-cure diseases. As potential therapeutics, peptides have many favorable chemical and pharmacological properties, ranging from their great diversity to their high affinity to various types of natural receptors. However, despite these and other advantages, they also have their pitfalls, such as a very limited stability in the organism. They have a short half-life and tend to be excreted from… Show more
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