Lipid peroxidation of kidney of the turtle Mauremys reevesii caused by cadmium

Dong, A.; Huo, Junfeng; Yan, Jing; Dong, Ailing; Liu, Biwang

doi:10.1007/s11356-020-11054-x

Cited by 7 publications

(2 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As one of the final products of lipid peroxidation, MDA content reflects the degree of oxidative damage suffered by important biomacromolecules, including phospholipids, glycolipids, and cholesterol (Parrish, 2013;Ayala et al, 2014). This damage leads to functional loss and disruption of homeostasis (Dong et al, 2021).…”

Section: Higher Oxidative Damage By Heat Waves In Low-latitude Turtlesmentioning

confidence: 99%

Heat wave induces oxidative damage in the Chinese pond turtle (Mauremys reevesii) from low latitudes

Tao

Ou²,

Wu³

et al. 2022

Front. Ecol. Evol.

View full text Add to dashboard Cite

IntroductionGlobal warming has led to frequent heat waves, causing global organisms to face severe survival challenges. However, the way in which heat waves threaten the fitness and survival of animals remains largely unclear. Oxidative damage and immunity are widely considered the link between heat waves and threats to animals.MethodsTo evaluate the oxidative damage caused by heat waves and to reveal the physiological resistance to heat waves by the antioxidant defense of animals from different latitudes, we exposed both high-latitude (Zhejiang) and low-latitude (Hainan) populations of Chinese pond turtle (Mauremys reevesii) to simulate heat waves and a moderate thermal environment for 1 week, respectively. Next, we compared the oxidative damage by malondialdehyde (MDA) and antioxidant capacity by superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and total antioxidant capacity (T-AOC) in the liver tissues and evaluated the innate immunity by serum complement protein levels (C3, C4) and lysozyme activity in plasma of turtles.Results and discussionWe found that heat waves significantly increased the content of MDA and the activity of CAT, whereas it decreased the activity of SOD, T-AOC, and GSH/GSSG in turtles from low latitudes. Furthermore, heat waves increased CAT activity but decreased GSH/GSSG in turtles from high latitudes. Although the turtles from high latitudes had higher levels of innate immunity, the heat waves did not affect the innate immunity of C3, C4, or lysozyme in either population. These results indicate that the low-latitude population suffered higher oxidative damage with lower antioxidant capacities. Therefore, we predict that Chinese pond turtles from low latitudes may be more vulnerable to heat waves caused by climate warming. This study reveals the physiological and biochemical resistance to heat waves in Chinese pond turtles from different latitudes and highlights the importance of integrative determination of fitness-related responses in evaluating the vulnerability of ectotherms from different latitudes to climate warming.

show abstract

Section: Higher Oxidative Damage By Heat Waves In Low-latitude Turtlesmentioning

confidence: 99%

Heat wave induces oxidative damage in the Chinese pond turtle (Mauremys reevesii) from low latitudes

Tao

Ou²,

Wu³

et al. 2022

Front. Ecol. Evol.

View full text Add to dashboard Cite

show abstract

“…Experimental research revealed alteration in macroautophagy regulating lipid storage and reduced expression of LDL receptor might be involved in cadmium induced dyslipidemia[Liu et al 2020, Rosales-Cruz et al 2018]. Moreover, considering cadmium could exhaust protein and glutathione-bound sulfhydryl groups, upregulation of lipid peroxidation might also participate in the underlying mechanism[Dong et al 2021].…”

mentioning

confidence: 99%

Association of blood cadmium and metabolic syndrome: a cross-sectional analysis of National Health and Nutrition Examination Survey 2017–2020

Xing

Wang

et al. 2022

Environ Sci Pollut Res

View full text Add to dashboard Cite

Previous ndings have reported the role of different types of heavy metals in cardiometabolic diseases. In the present research, we aim to evaluate the association between blood cadmium levels and MetS base on the large-sample NHANES data. Public availably data from NHANES 2017-2020 cycle was obtained. Participants were divided into MetS and non-MetS groups according to waist circumference (WC), triglyceride (TG), high-density lipoprotein (HDL), blood pressure (BP) and fasting plasma glucose (FPG) levels based on the National Cholesterol Education Program (NCEP) criteria. Student's t test, Mann-Whitney U test, and Chi-square test were performed for univariate analysis. Multivariate logistic analysis was performed to explore the relationship between blood cadmium and MetS and research ndings were presented in forest plot. We also investigated the association of blood cadmium and MetS in subgroups strati ed by age, gender and race. Population with MetS had signi cantly higher levels of blood cadmium compared with those without MetS [0.30 (0.18-0.54) vs. 0.24 (0.15-0.46) ug/L, p < 0.001]. Higher blood cadmium concentrations were also observed in participants with elevated WC, TG, BP and FPG compared with those with normal metabolic parameters. Multivariate logistic regression showed that one unit increasement of blood cadmium was associated with 1.25 times higher prevalence ratios for MetS after adjusting potential confounders (95% CI: 1.06-1.48, p = 0.0083). Strati ed multiple logistic regression analysis indicated that the positive association between blood cadmium and MetS remained signi cant in subjects less than 60 years old and female subgroup. In conclusion, the cross-sectional survey suggested the positive association between blood cadmium levels and risk for MetS, prospective research need to be conducted for further evaluation of the causal relationship between blood cadmium and MetS.

show abstract

Effects of Cadmium on Kidney Function of the Freshwater Turtles Mauremys reevesii

Dong

et al. 2022

Biol Trace Elem Res

View full text Add to dashboard Cite

Lipid peroxidation of kidney of the turtle Mauremys reevesii caused by cadmium

Cited by 7 publications

References 43 publications

Heat wave induces oxidative damage in the Chinese pond turtle (Mauremys reevesii) from low latitudes

Heat wave induces oxidative damage in the Chinese pond turtle (Mauremys reevesii) from low latitudes

Association of blood cadmium and metabolic syndrome: a cross-sectional analysis of National Health and Nutrition Examination Survey 2017–2020

Effects of Cadmium on Kidney Function of the Freshwater Turtles Mauremys reevesii

Contact Info

Product

Resources

About