Lipid nanoparticles: An advanced delivery system for quercetin

Abstract

Quercetin is a flavonoid with strong antioxidant activity considered as a potential drug candidate for number of chronic diseases; crude quercetin suffers from poor water solubility and consequently topical inactivity. Therefore, quercetin formulation within a suitable system that overcomes its solubility limitation is a matter of investigation. Many approaches were tested to improve quercetin delivery to skin. One effective approach is lipid nanocapsules. These nanoformulations are ideal in terms of average particle size and homogeneity (PDI). Hence, lipid nanoparticles are an attractive candidate for the encapsulation of quercetin for potent and effective drug delivery.