Lipid nanoparticle‐mediated RNA delivery for immune cell modulation
Emily H. Kim,
Sridatta V. Teerdhala,
Marshall S. Padilla
et al.
Abstract:Lipid nanoparticles (LNPs) have emerged as the preeminent nonviral drug delivery vehicles for nucleic acid therapeutics, as exemplified by their usage in the mRNA COVID‐19 vaccines. As a safe and highly modular delivery platform, LNPs are attractive for a wide range of applications. In addition to vaccines, LNPs are being utilized as platforms for other immunoengineering efforts, especially as cancer immunotherapies by modulating immune cells and their functionality via nucleic acid delivery. In this review, w… Show more
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