2022
DOI: 10.3390/nano12030377
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Lipid Nanomaterials for Targeted Delivery of Dermocosmetic Ingredients: Advances in Photoprotection and Skin Anti-Aging

Abstract: Despite the health benefits of the sun, overexposure to solar radiation without proper precautions can cause irreversible damage to exposed skin. In the search for balance between the risks and benefits of exposure to solar radiation in human health, a technological alternative was found, the incorporation of photoprotective products in lipid nanoparticulate systems for topical application. These nanometric systems have demonstrated several advantages when used as adjuvants in photoprotection compared to chemi… Show more

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Cited by 22 publications
(16 citation statements)
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References 120 publications
(169 reference statements)
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“…Among them, lipid nanoparticles (e.g., solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), liposomes, and oil-in-water (o/w) nanoemulsions) ( Figure 3 ) are particularly interesting, as they can be synthesized from lipid materials that comprise the skin (e.g., fatty acids; waxes; mono-, di-, and tri-glycerides; and phospholipids), offering great biocompatibility and biodegradability [ 55 , 56 , 57 ]. Lipid nanoparticles can also be surface-functionalized with aptamers for site-specific targeting [ 58 , 59 ] and show a modified-release profile [ 60 ], reducing the risk of toxicity ( Figure 4 ).…”
Section: Nanoparticle-related Therapies For Bccmentioning
confidence: 99%
“…Among them, lipid nanoparticles (e.g., solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), liposomes, and oil-in-water (o/w) nanoemulsions) ( Figure 3 ) are particularly interesting, as they can be synthesized from lipid materials that comprise the skin (e.g., fatty acids; waxes; mono-, di-, and tri-glycerides; and phospholipids), offering great biocompatibility and biodegradability [ 55 , 56 , 57 ]. Lipid nanoparticles can also be surface-functionalized with aptamers for site-specific targeting [ 58 , 59 ] and show a modified-release profile [ 60 ], reducing the risk of toxicity ( Figure 4 ).…”
Section: Nanoparticle-related Therapies For Bccmentioning
confidence: 99%
“…There are two types of UV filters used for photoprotection. Dermatologists classified UV filters as inorganic and organic agents [ 2 ]. Organic filters absorb a narrow band of ultraviolet radiation (UVR), whereas for inorganic filters, the interaction of absorption and scattering results in “wide spectrum” (UVA and UVB) protection ( Figure 1 ).…”
Section: Introductionmentioning
confidence: 99%
“…Consequently, the identification of commercially available cosmetics based on nanotechnology is quite challenging. Moreover, there is a recognized need for research into the efficacy and safety with precise guidelines for manufacturing, advertising, nanotoxicological testing, and safe use of nanocosmetics [ 27 , 28 , 33 , 36 , 37 ].…”
Section: Introductionmentioning
confidence: 99%