Lipid nanocarriers containing Passiflora edulis seeds oil intended for skin application

Krambeck, Karolline; Santos, Delfim; Otero-Espinar, Francisco J.; Lobo, José Manuel Sousa; Amaral, Maria Helena

doi:10.1016/j.colsurfb.2020.111057

Cited by 13 publications

(7 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…P. edulis seed extract was found to stimulate collagen production and inhibit elastin degradation, preserving skin moisture and elasticity [ 113 ]. Lipid nanoparticles containing passion fruit seed oil as a liquid lipid and glyceryl distearate as a solid lipid were deemed suitable for skin administration and could be incorporated into semi-solid formulations to enhance their skin applications [ 114 ].…”

Section: Medical Effects and Activities In Pharmacymentioning

confidence: 99%

Chemical Compositions, Pharmacological Properties and Medicinal Effects of Genus Passiflora L.: A Review

Nikolova,

Velikova,

Gentscheva

et al. 2024

Plants

View full text Add to dashboard Cite

Practically all aboveground plants parts of Passiflora vines can be included in the compositions of dietary supplements, medicines, and cosmetics. It has a diverse chemical composition and a wide range of biologically active components that determine its diverse pharmacological properties. Studies related to the chemical composition of the plant are summarized here, and attention has been paid to various medical applications—(1) anti-inflammatory, nephroprotective; (2) anti-depressant; (3) antidiabetic; (4) hepatoprotective; (5) antibacterial and antifungal; and (6) antipyretic and other. This review includes studies on the safety, synergistic effects, and toxicity that may occur with the use of various dietary supplements based on it. Attention has been drawn to its application in cosmetics and to patented products containing passionflower.

show abstract

Section: Medical Effects and Activities In Pharmacymentioning

confidence: 99%

Chemical Compositions, Pharmacological Properties and Medicinal Effects of Genus Passiflora L.: A Review

Nikolova,

Velikova,

Gentscheva

et al. 2024

Plants

View full text Add to dashboard Cite

show abstract

“…The NLC containing RO was prepared following a modified high shear homogenization technique [25,26] . Compritol 888 ATO (C888) was selected as the solid lipid component, while Rosehip oil (RO) was used as the liquid lipid phase.…”

Section: Preparation Of Nlcmentioning

confidence: 99%

Enhanced Topical Delivery of Rosehip Oil (RO) through Nanostructured Lipid Carriers (NLC)

Sağıroğlu

2024

Haydarpasa Numune Med J

View full text Add to dashboard Cite

Introduction: Rosehip oil (RO) is rich in bioactive constituents with potential for various formulations. This investigation aims to design and analyze Nanostructured Lipid Carriers (NLC) containing RO to protect its delicate components, prolong RO's shelf life, and enhance its permeability. Methods: The NLC formulation was created using high shear homogenization, with RO as the liquid lipid and Compritol 888 ATO (C888) as the solid lipid. A series of assessments was conducted to evaluate encapsulation effectiveness, particle size distribution, polydispersity index, zeta potential, ex vivo skin penetration, and stability. Results: The NLCs showed uniform spherical morphology, average particle sizes of 180 nm, PDI below 0.3, and zeta potential around -30 mV. High encapsulation efficiency was also observed. Ex vivo experiments indicated improved Quercetin retention in both Stratum Corneum (SC) and viable epidermis/dermis layers with NLC-encapsulated RO compared to RO alone. Stability assessments showed that the NLC formulation remained stable at 4°C for at least 90 days. Discussion and Conclusion: The findings support NLC's efficacy in delivering active compounds to the skin, presenting an encouraging alternative for treating skin conditions.

show abstract

“…Piceatannol and other stilbene compounds have been identified not only in ethanol and acetone extracts of P. edulis seed, but also in extracted seed oil [44], and P. edulis seed oil extracted by ultrasound showed tyrosinase inhibitory activity [75]. Furthermore, nanostructured lipid carrier-based hydrogels with P. edulis seed oil showed high tyrosinase inhibitory activity and low skin irritation; therefore, P. edulis seed oil has been considered for use as a cosmetic [76]. In human studies, most subjects noticed significant improvement in acne vulgaris after 8 weeks of application of a 10% P. edulis seed extract cream [77].…”

Section: Effect On Skinmentioning

confidence: 99%

Constituent Characteristics and Functional Properties of Passion Fruit Seed Extract

Kawakami¹,

Morinaga²,

Tsukamoto-Sen³

et al. 2021

Life

View full text Add to dashboard Cite

The genus Passiflora L. is widely cultivated in tropical and subtropical regions. The major species, Passiflora edulis Sims, is known as ‘passion fruit’ and is widely used in processed foods as well as eaten raw. P. edulis fruits are eaten for their pulp together with the seeds; however, the seeds are often discarded when used in processed foods. P. edulis seeds contain a variety of nutrients and functional components, and their industrial use is desirable from the perspective of waste reduction. Previous studies have analyzed the constituents of P. edulis and their physiological functions. P. edulis seeds contain various types of polyphenols, especially those rich in stilbenes (e.g., piceatannol). P. edulis seed extracts and isolated compounds from seeds have been reported to exhibit various physiological functions, such as antioxidant effects, improvement of skin condition, fat-burning promotion effects, and hypoglycemic effects. This review summarizes the nutritional characteristics, polyphenol content, and physiological functions of P. edulis seeds.

show abstract

Lipid nanocarriers containing Passiflora edulis seeds oil intended for skin application

Cited by 13 publications

References 36 publications

Chemical Compositions, Pharmacological Properties and Medicinal Effects of Genus Passiflora L.: A Review

Chemical Compositions, Pharmacological Properties and Medicinal Effects of Genus Passiflora L.: A Review

Enhanced Topical Delivery of Rosehip Oil (RO) through Nanostructured Lipid Carriers (NLC)

Constituent Characteristics and Functional Properties of Passion Fruit Seed Extract

Contact Info

Product

Resources

About