Lipid Levels as Predictors of Silent Myocardial Ischemia in a Type 2 Diabetic Population in Havana

Peña, Yamilé; Fernández-Britto, José Emilio; Bacallao, Jorge; Batista, Juan F.; Leon, Maria Lowella De

doi:10.37757/mr2012v14.n1.5

Cited by 8 publications

(1 citation statement)

References 24 publications

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“…Elevated levels of triglycerides, fasting and nonfasting, are also independent risk factors for CHD. Low HDL and elevated triglycerides have the highest rate of major coronary events, while serum cholesterol has been shown to be an established CHD risk factor [31,32]. ECG is a diagnostic test that can help identify the presence of coronary ischemia.…”

Section: Discussionmentioning

confidence: 99%

Patients with Achilles Tendon Rupture Are Prone to Develop Ventricular Arrhythmia

Gür

Yapıcı

Küçük

et al. 2023

JCM

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Background and Objectives: This study aimed to examine the ventricular repolarization (VR) disturbances of patients operated on for acute spontaneous Achilles tendon ruptures (ATRs), by comparing them with a healthy individual control group. Materials and Methods: Between June 2014 and July 2020, a total of 29 patients (28 males, 1 female; mean age: 40 ± 9.78 years; range, 21–66 years) who presented to the emergency department within the first three weeks of injury, and were diagnosed with acute spontaneous ATRs and treated with an open Krackow suture technique, were retrospectively analyzed. Fifty-two healthy individuals (47 males, 5 females; mean age: 39 ± 11.45 years; range, 21–66 years) were recruited as a control group from the cardiology outpatient clinic. Clinical data (demographic features and laboratory parameters (serum glucose, creatinine, hemoglobin, white blood cell count, and lipid profile)) and electrocardiograms (ECGs) were collected from medical records. ECGs were evaluated for heart rate and VR parameters of QRS width, QTc interval, cQTd interval, Tp-e interval, and Tp-e/QT ratio. The clinical data and these ECG parameters were compared between groups. Results: There was no statistically significant difference between groups, regarding clinical data (all p < 0.05). Among ECG parameters, heart rate, QRS width, QTc interval, and cQTd interval were similar between groups (all p < 0.05). There were two important statistically significant findings of this research: The mean Tp-e interval was longer (ATR group: 72.4 ± 24.7, control group: 58.8 ± 14.5, p: 0.01), and the Tp-e/QT ratio was higher (ATR group: 0.2 ± 0.1, control group: 0.16 ± 0.4, p: 0.027) in the ATR group. Conclusions: According to the ventricular repolarization disturbances found in this study, patients with ATR may be at a higher risk of ventricular arrhythmia than healthy people. As a result, ATR patients should be assessed for ventricular arrhythmia risk by an expert cardiologist.

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Section: Discussionmentioning

confidence: 99%

Patients with Achilles Tendon Rupture Are Prone to Develop Ventricular Arrhythmia

Gür

Yapıcı

Küçük

et al. 2023

JCM

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Molecular Imaging of Native Low-Density Lipoprotein by Near-Infrared Fluorescent Angioscopy in Human Coronary Plaques

Uchida¹,

Yoshida

Shimoyama

et al. 2016

The American Journal of Cardiology

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Low-density lipoprotein (LDL) is an important risk factor for coronary artery disease, but its localization within the human coronary arterial wall is poorly understood. Imaging of LDL in 30 coronary arteries excised from 15 subjects who underwent autopsy was performed using near-infrared fluorescent angioscopy system and using indocyanine green dye as a biomarker of LDL. The percentage incidence of LDL in 28 normal segments, 24 white plaques (early stage of plaque growth), and 21 yellow plaques (mature stage of plaque) classified by conventional angioscopy, was 14.2, 79.1 (p <0.01 vs normal segments and p <0.05 vs yellow plaques), and 28.5, respectively. Coronary near-infrared fluorescent angioscopy showed similar results in 7 patients in vivo. Our results suggested that LDL begins to deposit in the human coronary arterial wall in the early stage of atherosclerosis, increasingly deposits with plaque growth and decreases in the mature stage; and therefore, molecular therapy targeting LDL should be started before plaque maturation.

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Prevalencia de cardiopatía isquémica asintomática en pacientes con diabetes mellitus tipo 2

Paz

Lee-Tsai

et al. 2018

Revista Colombiana de Cardiología

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Lipid Levels as Predictors of Silent Myocardial Ischemia in a Type 2 Diabetic Population in Havana

Cited by 8 publications

References 24 publications

Patients with Achilles Tendon Rupture Are Prone to Develop Ventricular Arrhythmia

Patients with Achilles Tendon Rupture Are Prone to Develop Ventricular Arrhythmia

Molecular Imaging of Native Low-Density Lipoprotein by Near-Infrared Fluorescent Angioscopy in Human Coronary Plaques

Prevalencia de cardiopatía isquémica asintomática en pacientes con diabetes mellitus tipo 2

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