Lipid index changes in the blood serum of patients with hyperplastic and early neoplastic lesions in the ovaries

Abstract

Background: The authors used the lipid index (WL) to monitor lipid changes before and after surgery. The surgical operation performed was the simultaneous enucleation of a cystic tumor of the hilum ovarii in its entirety (with diagnosis of a simple cyst or teratoma adultum) in groups of 20 patients. Objectives: To compare the lipid index WL in the blood serum of patients undergoing surgery treatment at the following times: before and 7 days after surgery, and 6 and 12 months after surgery. Material and methods: The research material was the blood serum of women aged about 24 years. The authors divided the patients into 3 groups: two groups of 20 women and a control group. The concentrations of the lipid parameters were measured and the lipid index WL was calculated. Results: Statistically significant differences were found between the lipid index of serum from patients with diagnosed ovarian neoplasms and the index of serum from healthy subjects; differences were demonstrated in the postoperative period, particularly 6 and 12 months after surgery. Conclusions: The lipid index WL proved useful in diagnosing ovarian neoplasm (simple cysts and teratoma adultum) and in monitoring the postoperative period.

Lipid indices in women blood serum before and after the procedure of removal of mature ovarian teratoma

“…In the present research the usability of lipid indices was shown in women who underwent gynaecological surgeries during menopause [9] and with pathological changes within ovaries. The lipid index WS has recently been described, and it has been successfully used in ovarian cancer diagnostics [12,17,18].…”